Results 131 to 140 of about 2,463 (224)

GSK3α‐mediated regulation of the RNA demethylase fat mass and obesity‐associated protein (FTO) during murine spermatogenesis

open access: yesThe FEBS Journal, EarlyView.
FTO regulates mRNA stability and translational efficiency through its m6A‐demethylation activity. GSK3 functions as an upstream regulator of FTO, leading to its inhibition via phosphorylation. In male germ cells, FTO activity is kept in check by GSK3α.
Neha Choudhari   +7 more
wiley   +1 more source

Heterodonty in the teeth of the turiasaurian sauropod from Angeac‐Charente (Early Cretaceous, southwestern France): Comparison of anatomical and geometric morphometric approaches

open access: yesJournal of Anatomy, EarlyView.
Turiasaurian teeth from Angeac‐Charente exhibit five dental morphotypes and reveal clear heterodonty and anteroposterior size gradient. Qualitative comparative anatomy quickly and efficiently identifies morphotypes, while 3D geometric morphometrics combined with machine learning refine ambiguous cases, demonstrating that qualitative and quantitative ...
Clémence Le Gouellec   +7 more
wiley   +1 more source

Advanced imaging and multi‐omics to characterize cardiomyocyte ageing and its electrocardiographic imprint in PKP2 arrhythmogenic cardiomyopathy

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend We used a murine model of cardiomyocyte‐specific conditional knockout of plakophilin 2 (PKP2cKO, middle panel). Using advanced imaging technology, we unveiled distinct hallmarks of premature ageing in PKP2cKO cardiomyocytes, including DNA damage and loss of repressed heterochromatin at the nuclear periphery, and mitochondrial ...
Giorgia Bertoli   +12 more
wiley   +1 more source

Recognizing distance-count matrices. [PDF]

open access: yesPLoS One
Boldi P, Prezioso C, Furia F, Stewart I.
europepmc   +1 more source

Bayesian optimized color filter: A fast method for segmentation of plant phenotypes from 3D point cloud images

open access: yesThe Plant Phenome Journal, Volume 9, Issue 1, December 2026.
Abstract Multispectral three‐dimensional (3D) imaging offers substantial potential for plant phenotyping, yet manual segmentation of plant organs remains a bottleneck in breeding programs. We developed a color‐based filtering workflow for faba bean (Vicia faba L.) point clouds that optimizes lower and upper thresholds of spectral indices and broadband ...
Lennart Scheer   +6 more
wiley   +1 more source

Improving AI Explainability Through Design of Experiments

open access: yesJournal of Chemometrics, Volume 40, Issue 11, November 2026.
ABSTRACT In artificial intelligence (AI), the complexity of many models and processes surpasses human understanding, making it challenging to determine why a specific prediction is made. This lack of transparency is particularly problematic in critical fields like healthcare, where trust in a model's predictions is paramount.
Alexandra Stadler   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy