Results 161 to 170 of about 93,645 (215)
Cartilage-on-Cartilage Cyclic Loading Induces Mechanical and Structural Damage
Journal of the Mechanical Behavior of Biomedical Materials, 2019 Cartilage breaks down during mechanically-mediated osteoarthritis (OA). While previous research has begun to elucidate mechanical, structural and cellular damage in response to cyclic loading, gaps remain in our understanding of the link between cyclic cartilage loading and OA-like mechanical damage.
Corinne R Henak, Kelly Vazquez
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Cartilage damage: clinical approach
Minerva Orthopedics, 2022Cartilage damage is a frequent joint affection and may have various etiologies. Degenerative and traumatic lesions are by far prevalent and are not easy to treat due to the characteristics of cartilage tissue, which has poor repair capacity. Nevertheless, clinical management for cartilage damage is based on great therapeutic possibilities that ...
FARI G. +8 more
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COX-2, NO, and cartilage damage and repair
Current Rheumatology Reports, 2000The production of nitric oxide (NO) and prostaglandin E2 (PGE(2)) is increased in human osteoarthritis-affected cartilage. These and other inflammatory mediators are spontaneously released by OA cartilage explants ex vivo. The excessive production of nitric oxide inhibits matrix synthesis, and promotes its degradation.
A R, Amin +3 more
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Susceptibility of Cartilage to Damage by Immunological Inflammation
International Archives of Allergy and Applied Immunology, 2009Injection of ovalbumin into subcutaneous air pouches prepared on the backs of rats previously sensitised to the antigen resulted in the induction of a small and transient accumulation of inflammatory fluid with a predominantly polymorph cell infiltrate.
A Y, Al-Duaij +4 more
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Calcium crystals and cartilage damage
Current Opinion in Rheumatology, 1996Recent advances in understanding the pathogenesis and mechanisms whereby calcium crystals contribute to cartilage damage are highlighted in this review. Studies that help elucidate pathologic crystal formation in cartilage are discussed. The effect of calcium pyrophosphate dihydrate crystals on the progression of joint degeneration in vivo is noted ...
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Biological treatment of joint cartilage damage
Scandinavian Journal of Medicine & Science in Sports, 2000The structure and composition of articular cartilage provides unique mechanical properties which effectively dampen and distribute loads during weightbearing. Acute traumatic damage to the articular cartilage destroys the original structure and composition of the articular cartilage and impairs its function.
A, Tyyni, J, Karlsson
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On Mechanical Mechanism of Damage Evolution in Articular Cartilage
Materials Science and Engineering C, 2017Superficial lesions of cartilage are the direct indication of osteoarthritis. To investigate the mechanical mechanism of cartilage with micro-defect under external loading, a new plain strain numerical model with micro-defect was proposed and damage evolution progression in cartilage over time has been simulated, the parameter were studied including ...
Yu-tao Men, Chun-Qiu Zhang
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Classification of Cartilage Damage
1988The aim of classification of injuries or diseases is to categorise certain types of lesions according to specific characteristics such as mechanism of injury, location, type, extent and depth of lesion and to separate them according to definite criteria in order to be able to determine the clinical management.
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Decellularized Caprine Conchal Cartilage toward Repair and Regeneration of Damaged Cartilage
ACS Applied Bio Materials, 2019Repair and regeneration of nasal and auricular cartilage thrust significant challenges in reconstructive surgery. The burgeoning clinical requirement is yet to endorse a satisfactory cartilage replacement matrix. In this regard, we have bioengineered cross-linked decellularized caprine conchal cartilage (DC) as biocompatible, durable, and nontoxic ...
Piyali Das +6 more
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