Results 11 to 20 of about 93,645 (215)

Spectroscopic photoacoustic imaging of cartilage damage [PDF]

Osteoarthritis and Cartilage, 2021
Osteoarthritis (OA) is a chronic joint disease characterized by progressive degradation of cartilage. It affects more than 10% of the people aged over 60 years-old worldwide with a rising prevalence due to the increasingly aging population. OA is a major source of pain, disability, and socioeconomic cost.
M. Wu, B.C.J. van Teeffelen, K. Ito, F.N. van de Vosse, R.P.A. Janssen, C.C. van Donkelaar, R.G.P. Lopata   +6 more
openaire   +2 more sources

The ankle cartilage cascade: incremental cartilage damage in the ankle joint [PDF]

Knee Surgery, Sports Traumatology, Arthroscopy, 2021
AbstractLevel of evidence Editorial, Level V.
Jari Dahmen, Jon Karlsson, Sjoerd A. S. Stufkens, Gino M. M. J. Kerkhoffs   +3 more
openaire   +3 more sources

Cartilage and bone damage in rheumatoid arthritis [PDF]

Rheumatology, 2018
Rheumatoid arthritis (RA), which is a chronic inflammatory disease with a multifactorial aetiology, leads to partial or permanent disability in the majority of patients. It is characterised by persistent synovitis and formation of pannus, i.e. invasive synovial tissue, which ultimately leads to destruction of the cartilage, subchondral bone, and soft ...
Ostrowska, Monika, Maśliński, Włodzimierz, Prochorec-Sobieszek, Monika, Nieciecki, Michał, Sudoł-Szopińska, Iwona   +4 more
openaire   +2 more sources

Autofluorescence Lifetime Reports Cartilage Damage in Osteoarthritis [PDF]

Scientific Reports, 2020
AbstractOsteoarthritis (OA) is the most common arthritis and its hallmark is degradation of articular cartilage by proteolytic enzymes leading to loss of joint function. It is challenging to monitor the status of cartilage in vivo and this study explores the use of autofluorescence lifetime (AFL) measurements to provide a label-free optical readout of ...
João L. Lagarto, Mohammad B. Nickdel, Douglas J. Kelly, Andrew Price, Jagdeep Nanchahal, Chris Dunsby, Paul French, Yoshifumi Itoh   +7 more
openaire   +3 more sources

Femoral Cartilage Ultrasound Echo Intensity Associates with Arthroscopic Cartilage Damage [PDF]

Ultrasound in Medicine & Biology, 2021
This study compared quantitative cartilage ultrasound metrics between people with (n = 12) and without (n = 12) arthroscopic cartilage damage after anterior cruciate ligament injury (age, 24.9 ± 3.7 y; sex, 33% female, 67% male; days since injury = 50 ± 52).
Harkey, Matthew S., Little, Erin, Thompson, Mikaela, Zhang, Ming, Driban, Jeffrey B., Salzler, Matthew J.   +5 more
openaire   +3 more sources

Biomaterials in Cartilage Damage

Wiadomości Lekarskie
Aim: Cartilage tissue degradation is a common symptom of diseases affecting the musculoskeletal system. Impairment of its function can occur due to numerous factors, both external and internal. Thanks to advances in imaging techniques, identifying pathologies in cartilage tissue is becoming increasingly common, leading to a search for optimal ...
Marta Żerebiec, Weronika Woźnica, Natalia Kołodyńska, Zuzanna Kołodyńska, Natasza Jankowska, Lena Sobiech, Vivek Vasudevan, Katarzyna Jóźwik, Karolina Turżańska, Małgorzata Drelich   +9 more
openaire   +3 more sources

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Imaging of cartilage damage

Journal of Cartilage & Joint Preservation
Introduction: Cartilage damage is a common cause of joint pain and disability. Familiarity with common injury patterns and associated terminology is critical for appropriate treatment and communication. Objectives: The goal of this narrative review is to describe the imaging features of cartilage damage and highlight the correlation with arthroscopic ...
Colin Strickland, Mohammad Ibrahim, Eric McCarty   +2 more
openaire   +2 more sources

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source