Results 41 to 50 of about 356,143 (297)

Bioinspired Hydrogels with Broadly Programmable Mechanics for Soft‐Tissue Interfaces

open access: yesAdvanced Functional Materials, EarlyView.
Sea cucumber‐inspired gelatin hydrogels are formed by directional freezing and mechanically programmed through subsequent ionic treatment. Multiscale characterization and modeling link ion‐regulated chain interactions to directional load transfer within the aligned hierarchical architecture.
Youchao Teng   +20 more
wiley   +1 more source

Are ankle chondrocytes from damaged fragments a suitable cell source for cartilage repair? [PDF]

open access: yes, 2010
To characterize the post-expansion cartilage-forming capacity of chondrocytes harvested from detached fragments of osteochondral lesions (OCLs) of ankle joints (Damaged Ankle Cartilage Fragments, DACF), with normal ankle cartilage (NAC) as ...
Miot, S   +29 more
core   +1 more source

Bone Organoids Across the Development‐to‐Remodeling Continuum: From Tissue Formation to Functional Competence and Translation

open access: yesAdvanced Healthcare Materials, EarlyView.
Mineralization alone does not establish a mature bone organoid. This Review integrates biological foundations, materials design, adaptive remodeling, and translational validation through the development‐to‐remodeling continuum (DRC). By separating biological functions from the evidence supporting them, the framework exposes critical gaps in current ...
Xijie Tang   +4 more
wiley   +1 more source

Biomechanics of osteochondral graft insertion : : cartilage damage and protection strategies [PDF]

open access: yes, 2014
Osteochondral graft repair is one of the most effective surgical treatments for focal cartilage defects. During such surgery, the load applied on the graft during impact insertion can result in damage to its articular cartilage, and therefore be ...
Su, Wei-i Alvin
core  

Fabrication of Aligned Polycaprolactone Nanofibrillar Bundles to Control Cell‐Mediated Collagen Deposition in Engineered Cartilage

open access: yesAdvanced Materials, EarlyView.
Melt electrofibrillation (MEF) enables the fabrication of nanofibrillar PCL scaffolds with defined architectures that guide cellular alignment and retention during cartilage tissue engineering. Unlike conventional melt electrowriting, MEF consistently directs collagen type II‐rich extracellular matrix organization, providing a tunable platform to ...
Alba Pueyo Moliner   +10 more
wiley   +1 more source

Survival Rates of Various Autologous Chondrocyte Grafts and Concomitant Procedures. A Prospective Single-Center Study over 18 Years

open access: yesCell Transplantation, 2019
Seven different autologous chondrocyte implantation (ACI) grafts were used consecutively over a period of 18 years for the treatment of cartilage lesions in the knees.
David Martinčič   +2 more
doaj   +1 more source

Nanoassemblies of Tissue-Reactive, Polyoxazoline Graft-Copolymers Restore the Lubrication Properties of Degraded Cartilage

open access: yes, 2017
Osteoarthritis leads to an alteration in the composition of the synovial fluid, which is associated with an increase in friction and the progressive and irreversible destruction of the articular cartilage.
Marcy Zenobi-Wong (116962)   +15 more
core   +1 more source

A Critical Review on the Evolution of Chitosan‐Based Injectable Hydrogels in Bone Regeneration

open access: yesAdvanced Materials Interfaces, EarlyView.
The graphical illustration depicts hydrogel formulation using chitosan and biocompatible cross‐linkers, major advantages, and incorporation of cells, osteoinductive factors, and therapeutic drugs. Following injection, pH‐responsive gelation enables controlled drug release, promotes cell recruitment and osteogenic differentiation, enhances extracellular
Shivani Santosh Sakhrani   +2 more
wiley   +1 more source

Percutaneous cartilage injection: A prospective animal study on a rabbit model

open access: yesJournal of Otolaryngology - Head and Neck Surgery, 2013
Background Cartilage grafting is a useful technique in nasal reconstruction. Implantation of a whole graft is usually done through an incision. Crushed cartilage can also be used. Injection of cartilage could be an alternative to implantation.
Olivier X Beaudoin   +2 more
doaj   +1 more source

Imaging of cartilage repair procedures

open access: yesIndian Journal of Radiology and Imaging, 2014
The rationale for cartilage repair is to prevent precocious osteoarthritis in untreated focal cartilage injuries in the young and middle-aged population.
Darshana Sanghvi   +2 more
doaj   +1 more source

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