Results 91 to 100 of about 337,591 (267)

The Republic of Ignorance

open access: yes, 2016
“When did ignorance become a point of view?” the cartoon character Dilbert once asked. It’s a question that has become increasingly resonant these days—especially in our public life, and especially in our political campaigns in which elected officials ...
DeNicola, Daniel R.
core  

REPRESENTASI SEPAK BOLA DALAM MICE CARTOON EDISI KOMENTATOR SEPAK BOLA: ANALISIS MULTIMODALITAS TERHADAP KOMIK KARTUN [PDF]

open access: yes, 2014
Komik merupakan bacaan yang menghibur dan mampu membangkitkan imajinasi seseorang. Salah satu komik Indonesia yang cukup menarik adalah Mice Cartoon. Dalam Mice cartoon terdapat dua unsur yaitu verbal dan visual yang layak untuk diteliti.
Ayuwandari, Ike
core  

De Novo Design and Directed Evolution Refinement of Mirror‐Image Protein Binders Targeting Interleukin‐4

open access: yesAdvanced Science, EarlyView.
This study presents the de novo design and directed evolution of a mirror‐image D‐protein inhibitor targeting human interleukin‐4 (IL‐4). The engineered molecule exhibits nanomolar binding affinity for IL‐4 and effectively inhibits IL‐4–mediated signaling.
Liqing Xu   +7 more
wiley   +1 more source

Functional Analysis of Ligand‐Gated Chloride Channels in a Cnidarian Sheds Light on the Evolution of Inhibitory Signaling

open access: yesAdvanced Science, EarlyView.
We uncover a large variety of putative inhibitory ligand‐gated ion channels (LGICs) in the phylum Cnidaria, the sister group to all bilaterian animals. Phylogenetic analysis suggests a complex evolutionary history of inhibitory LGICs with diverse neurotransmitter ligands.
Abhilasha Ojha   +13 more
wiley   +1 more source

Technique, genre ou médium ?

open access: yesAppareil, 2016
« Manga », « cartoon », « film d’animation », autant de locutions pour désigner ce que la langue française a, à partir des années 1910-1920, choisi d’unifier sous le terme générique de « dessin animé ».
Jean-Baptiste Massuet
doaj   +1 more source

PENGARUH FREKUENSI MENONTON FILM KARTUN KEKERASAN NARUTO TERHADAP PERILAKU IMITASI PADA ANAK-ANAK (Studi pada Siswa Kelas 5 A, B, C SDN Lowokwaru 1 Malang) [PDF]

open access: yes, 2009
Television is a system storytelling centralization. station of Television in Indonesia in carrying out broadcast has specified event pattern either vertically that is from hour clock to hour clock and also horizontally that is day after day.
SARI, IKA PURNAMA
core  

ADOLESCENT CARTOON [PDF]

open access: yesJournal of Paediatrics and Child Health, 2011
Azzopardi, P, Sawyer, S
openaire   +3 more sources

Cryo‐EM Structure Guided Engineering of Botulinum Neurotoxin A With Advanced Receptor Binding Affinity and Therapeutical Benefits

open access: yesAdvanced Science, EarlyView.
The butterfly unfolded wing in an open form structure of botulinum neurotoxin type A (BoNT/A) at physiological‐state was confirmed at 2.85 Å resolution by cryo‐electron microscopy (cryo‐EM). Structure‐guided protein engineering significantly enhanced the receptor‐binding affinity, therapeutic efficacy, and safety of the engineered toxin variants ...
Wenrui Wang   +16 more
wiley   +1 more source

Delivery of Pleckstrin‐Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis

open access: yesAdvanced Science, EarlyView.
Current therapies curb tumor growth but not metastasis. Obscurin, a giant metastasis suppressor lost in breast cancer, restrains PI3K/Akt signaling but is impractical to restore. We deploy a mini‐obscurin, comprising the obscurin‐PH‐domain, which sequesters PI3K‐p85, potently suppressing invasion and metastasis.
Matthew Eason   +12 more
wiley   +1 more source

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