Results 41 to 50 of about 1,208,680 (158)
Discordance of Dopaminergic Dysfunction and Subcortical Atrophy by α‐Synuclein Status in Sporadic and Genetic Parkinson's Disease
Movement Disorders, Volume 41, Issue 5, Page 1101-1113, May 2026.Abstract Background
Parkinson's disease (PD) is characterized by predominantly neuronal α‐synuclein pathology and dopaminergic dysfunction. Cerebrospinal fluid (CSF) seeding amplification assays (SAA) detect α‐synuclein aggregates in vivo, but not all patients with PD have a positive SAA.Michael Tran Duong, Sandhitsu R. Das, Pulkit Khandelwal, Joaquin A. Vizcarra, Yue Li, Long Xie, Paul A. Yushkevich, Leslie M. Shaw, Jacob G. Dubroff, Parkinson's Progression Markers Initiative, Kenneth Marek, Shirley Lasch, Caroline Tanner, Tanya Simuni, Christopher Coffey, Karl Kieburtz, Renee Wilson, Brit Mollenhauer, Site Investigator, Douglas Galasko, Site Investigator, Tatiana Foroud, Lana Chahine, Andrew Siderowf, John Seibyl, Arthur Toga, Andrew Singleton, Daniel Weintraub, John Trojanowski, Leslie Shaw, Duygu Tosun‐Turgut, Kathleen Poston, Susan Bressman, Kalpana M. Merchant, Werner Poewe, Todd Sherer, Sohini Chowdhury, Mark Frasier, Catherine Kopil, Anna Naito, Vanessa Arnedo, Ray Dorsey, Cynthia Casaceli, Imaging Core, Nichole Daegele, Justin Albani1 Statistics Core, Chelsea Caspell‐Garcia, Liz Uribe, Eric Foster, Jeff Long, Nick Seedorff, Karen Crawford, Danielle Elise Smith, Paola Casalin, Giulia Malferrari, Cheryl Halter, David Russell, Stewart Factor, Penelope Hogarth, David Standaert, Amy Amara, Robert Hauser, Joseph Jankovic, Matthew Stern, Shu‐Ching Hu, Gretchen Todd, Rachel Saunders‐Pullman, Irene Richard, Marie H Saint‐Hilaire, Klaus Seppi, Holly Shill, Hubert Fernandez, Claudia Trenkwalder, Wolfgang Oertel, Daniela Berg, Kathrin Brockman, Isabel Wurster, Liana Rosenthal, Yen Tai, Nicola Pavese, Paolo Barone, Stuart Isaacson, Alberto Espay, Dominic Rowe, Melanie Brandabur, James Tetrud, Grace Liang, Alex Iranzo, Eduardo Tolosa, Karen Marder, Maria de Arriba Sanchez, Leonidis Stefanis, Maria Jose Marti, Javier Ruiz Martinez, Jean‐Christophe Corvol, Jan O Assly, Salima Brillman, Nir Giladi, Debra Smejdir, Julia Pelaggi, Farah Kausar, Linda Rees, Barbara Sommerfield, Madeline Cresswell, Courtney Blair, Karen Williams, Grace Zimmerman, Stephanie Guthrie, Ashlee Rawlins, Leigh Donharl, Christine Hunter, Baochan Tran, Abigail Darin, Carly Linder, Marne Baca, Heli Venkov, Cathi‐Ann Thomas, Raymond James, Beatrice Heim, Paul Deritis, Fabienne Sprenger, Deborah Raymond, Diana Willeke, Zoran Obradov, Jennifer Mule, Nancy Monahan, Katharina Gauss, Deborah Fontaine, Daniel Szpak, Arita McCoy, Becky Dunlop, Laura Marie Payne, Susan Ainscough, Lisbeth Carvajal, Rebecca Silverstein, Kristy Espay, Madelaine Ranola, Elisabet Mondragon Rezola, Helen Mejia Santana, Maria Stamelou, Alicia Garrido, Stephanie Carvalho, Anne Grete Kristiansen, Krista Specketer, Anat Mirlman, Maurizio Facheris, Holly Soares, Mark A. Mintun, Jesse Cedarbaum, Peggy Taylor, Danna Jennings, Lawrence Slieker, Brian McBride, Colin Watson, Etienne Montagut, Zulfiqar Haider Sheikh, Baris Bingol, Remi Forrat, Pablo Sardi, Tanya Fischer, Alastair D. Reith, Jan Egebjerg, Lone Frydelund Larsen, Nathalie Breysse, Didier Meulien, Barbara Saba, Vera Kiyasova, Chris Min, Thomas McAvoy, Robert Umek, Philip Iredale, Jeremy Edgerton, Susan De Santi, Christian Czech, Frank Boess, Jeffrey Sevigny, Thomas Kremer, Igor Grachev, Kaplana Merchant, Andreja Avbersek, Pierandrea Muglia, Alexandra Stewart, Rene Prashad, Johannes Taucher, Andrew Siderowf, David A. Wolk, Ilya M. Nasrallah +186 morewiley +1 more sourceThe oral mucosal and salivary microbial community of Behçet's syndrome and recurrent aphthous stomatitis. [PDF]
, 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is ...Bergmeier, LA, Noha Seoudi, Bruce Paster, Farida Fortune, Paster, B, Francis Drobniewski, Lesley A. Bergmeier, Drobniewski, F, Fortune, F, Seoudi, N +9 morecore +1 more sourceThe Symptoms and Impacts Experienced by Healthcare Professionals as Second Victims After a Safety Incident: A Scoping Review
Journal of Advanced Nursing, Volume 82, Issue 5, Page 4538-4592, May 2026.ABSTRACT Aim
This study aimed to describe the types of psychological and physical symptoms experienced by healthcare professionals who became second victims after a patient safety incident and the impact of the incident on their social and professional lives. Design
Scoping review.Laura Jukarainen, Sanu Mahat, Saija Koskiniemi, Tiina Syyrilä, Albert W. Wu, Virpi Jylhä, Marja Härkänen +6 morewiley +1 more sourceInhibition of the NLRP3 Inflammasome With MCC950 Improves Gut Health in Huntington's Disease Mice
Journal of Neurochemistry, Volume 170, Issue 4, April 2026.The NLRP3 inflammasome in HD (Huntington's disease) peripheral pathology (in gastrointestinal complications) is vastly unexplored. In this preclinical study, non‐invasive readouts of gut function assessment revealed that inhibiting NLRP3 inflammasome by chronic administration of MCC950 by oral route softened the faecal pellets, improved faecal output ...Sujan Kumar Sarkar, Millicent N. Ekwudo, Da Lu, Bethany Masson, Pamudika Kiridena, Nicholas van de Garde, Thibault Renoir, James E. Vince, Veerasikku Gopal Deepagan, Anthony J. Hannan, Carolina Gubert +10 morewiley +1 more sourceSafety and efficacy of a feed additive consisting of a proanthocyanidin‐rich dry extract from the fruit of Vaccinium macrocarpon Aiton (cranberry extract) for dogs and cats (ACEL pharma S.r.l.)
EFSA Journal, Volume 24, Issue 4, April 2026.Abstract
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of a proanthocyanidin‐rich dry extract obtained from the fruit of Vaccinium macrocarpon Aiton (cranberry extract) when used as a sensory feed additive for dogs and cats. The additive is not currently authorised for use in EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Roberto Edoardo Villa, Giovanna Azimonti, Eleftherios Bonos, Henrik Christensen, Mojca Durjava, Ronette Gehring, Boet Glandorf, Maryline Kouba, Marta López‐Alonso, Francesca Marcon, Carlo Nebbia, Alena Pechová, Miguel Prieto‐Maradona, Katerina Theodoridou, Maria de Lourdes Bastos, Emilio Benfenati, Paul Brantom, Andrew Chesson, Secundino López‐Puente, Josef Schlatter, Johannes Westendorf, Maria Dulak‐Lis, Jordi Ortuño, Alberto Navarro Villa, Paola Manini, Birgit Dusemund +26 morewiley +1 more sourceCLINICAL, HISTOPATHOLOGICAL, AND MOLECULAR CHARACTERIZATION OF CARVAJAL SYNDROME WITH ORAL MANIFESTATIONS
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2019 Introduction Carvajal syndrome is characterized by woolly hair, striated palmoplantar keratoderma and left-sided ventricular cardiomyopathy. It is inherited as an autosomal recessive disorder due to a homozygous mutation in the gene coding for desmoplakin, which truncates the C-terminal of the protein and maps to chromosome 6p24. Signs and symptoms of Dr. Colby Haines, Dr. Jennie Ison, Dr. John Fantasia, Dr. Kathleen Schultz +3 moreopenaire +1 more sourceDemystifying fungal systematics: A gateway to fungal literacy and societal/ecological relevance through familiar species
PLANTS, PEOPLE, PLANET, Volume 8, Issue 2, Page 499-515, March 2026.Fungal systematics can feel overwhelming given the vast species diversity within this kingdom, with numerous subgroups at every taxonomic rank. This often creates a disconnect between the undertsnidng of fungal taxonomic diversity and their societal relevance.Anna Vaiana, Francis Martin, Rasmus Kjøller, Toby Spribille, Garima Singh +4 morewiley +1 more sourceCarvajal syndrome: A variant of Naxos disease in two Saudi siblings
Nigerian Journal of Experimental and Clinical Biosciences, 2013 Naxos disease is a recessively inherited condition characterized by woolly hair, palmoplantar keratosis and arrhythmogenic right ventricular cardiomyopathy. A variant of this predominantly involving left ventricle has been termed as Carvajal Syndrome. We report two cases in a Saudi family admitted in our Pediatric Intensive Care Unit.Yusuf Parvez, AbdulAziz Al-Hassanopenaire +1 more sourceMortality Patterns and Phenotypic Clusters in Trisomy 13: A Population‐Based Study From Japan
American Journal of Medical Genetics Part A, Volume 200, Issue 2, Page 329-338, February 2026.ABSTRACT
Trisomy 13, the third most common autosomal trisomy after trisomy 21 and trisomy 18, is associated with a significantly high infant mortality rate. However, large‐scale studies examining causes of death in trisomy 13 remain scarce. Therefore, we aimed to better understand the mortality patterns.Narumi Kato, Naho Morisaki, Akinori Moriichi +2 morewiley +1 more source