Results 111 to 120 of about 44,151 (306)
Рациональная фармакотерапия в кардиологии, 2016 Aim. To study clinical equivalence of original (DilatrendR, ≪Hoffmann-La Roche≫, Switzerland) and of generic (VedicardolR, ≪Synthesis≫, Russia) carvedilols with estimation of their serum level.
E. I. Bambysheva +5 more
doaj +1 more source
Alimentary Pharmacology &Therapeutics, EarlyView.There is no evidence of a difference between carvedilol 12.5 mg daily and VBL in the primary prevention of variceal bleeding in patients with cirrhosis and medium‐to large‐sized oesophageal varices. Carvedilol has no untoward safety concerns, is well tolerated, cost‐saving and potentially cost‐effective and is the preferred first‐line primary ...
Dhiraj Tripathi +205 more
wiley +1 more source
Progress on the development of Class A GPCR‐biased ligands
British Journal of Pharmacology, EarlyView.Class A G protein‐coupled receptors (GPCRs) continue to garner interest for their essential roles in cell signalling and their importance as drug targets. Although numerous drugs in the clinic target these receptors, over 60% GPCRs remain unexploited. Moreover, the adverse effects triggered by the available unbiased GPCR modulators, limit their use and
Paula Morales +20 more
wiley +1 more source
Drug Design, Development and Therapy, 2019 Aim To investigate the effect of carvedilol on liver fibrosis and hepatic sinusoidal capillarization in mice with carbon tetrachloride (CCl4)-induced fibrosis. Methods A liver fibrosis mouse model was induced by intraperitoneal CCl4 injection for 8 weeks.
Ying Wu +5 more
semanticscholar +1 more source
International Journal of Molecular Sciences, 2020 Catecholamines function via G protein-coupled receptors, triggering an increase in intracellular levels of 3′,5′-cyclic adenosine monophosphate (cAMP) in various cells.
M. Choi +6 more
semanticscholar +1 more source
Carvedilol induces endogenous hydrogen sulfide tissue concentration changes in various mouse organs [PDF]
, 2011 Carvedilol, a third generation non-selective adrenoreceptor blocker, is widely used in cardiology. Its action has been proven to reach beyond adrenergic antagonism and involves multiple biological mechanisms.
Góralska, Marta +5 more
core +1 more source
Clinical Endocrinology, EarlyView.ABSTRACT Objective Managing gastrointestinal symptoms in patients with phaeochromocytoma and paraganglioma (PPGL) is challenging due to the risk of catecholaminergic crisis with many commonly prescribed medications, especially in functional tumours.
Monica Majumder +5 more
wiley +1 more source
An overview of the management of Congestive Heart Failure in Malta [PDF]
, 2004 Background: In July 2003 the National Institute of Clinical Excellence (NICE) issued guidelines on the management of congestive heart failure. We set out to assess the management of congestive heart failure in St. Luke's Hospital (SLH), Malta.
Camilleri, Nicola +2 more
core
Use of carvedilol in hypertension: an update
Vascular Health and Risk Management, 2012 β-blockers are effective antihypertensive agents and, together with diuretics, have been the cornerstone of pioneering studies showing their benefits on cardiovascular morbidity and mortality as a consequence of blood pressure reduction in patients with hypertension.
Gastone Leonetti, Colin Gerard Egan
openaire +3 more sources
Diabetes, Obesity and Metabolism, EarlyView.Abstract Heart failure (HF) is a major health problem, and preventing the onset of heart failure could have large cost implications for healthcare systems globally. Screening for heart failure and its precursor, left ventricular dysfunction, could allow patients to receive therapies shown to reduce the risk of incident heart failure, such as ACE ...
Pardeep S. Jhund
wiley +1 more source