Results 141 to 150 of about 44,151 (306)

Effect of particle size on oral absorption of carvedilol nanosuspensions: in vitro and in vivo evaluation

open access: yesInternational Journal of Nanomedicine, 2015
Dandan Liu,1 Hao Pan,2 Fengwei He,1 Xiaoyu Wang,3 Jinyu Li,3 Xinggang Yang,3 Weisan Pan31Department of Pharmaceutical Engineering, School of Biomedical and Chemical Engineering, Liaoning Institute of Science and Technology, Benxi, People’s Republic
Liu DD   +6 more
doaj  

Carvedilol-Afforded Protection against Daunorubicin-Induced Cardiomyopathic Rats In Vivo: Effects on Cardiac Fibrosis and Hypertrophy [PDF]

open access: yes, 2011
Anthracyclines, most powerful anticancer agents, suffer from their cardiotoxic effects, which may be due to the induction of oxidative stress. Carvedilol, a third-generation, nonselective β-adrenoreceptor antagonist, possesses both reactive oxygen ...
Arozal, Wawaimuli   +12 more
core   +3 more sources

The Beta‐Blocker Pharmacogenetic Puzzle: More Pieces of Evidence for Pharmacodynamic Candidate Variants

open access: yesClinical and Translational Science, Volume 18, Issue 5, May 2025.
ABSTRACT Previous pharmacogenetic findings for beta‐blocker pharmacodynamic candidate genes (ADRB1, ADRB2, ADRA2C, GRK4, and GRK5) have been inconsistent. Therefore, the purpose of this study was to determine whether interactions of pharmacodynamic variants with beta‐blocker exposure significantly associated with survival in patients with heart failure
Jasmine A. Luzum   +5 more
wiley   +1 more source

Dilated cardiomyopathy in childhood [PDF]

open access: yes, 2000
Dilated Cardiomyopathy is an uncommon disease in children but morbidity and mortality in affected patients are high. This review discuses clinical presentation, diagnosis, medical management and prognosis of the condition, with an emphasis on recent ...
Franklin, O.M.
core  

Impact of initiating carvedilol before angiotensin-converting enzyme inhibitor therapy on cardiac function in newly diagnosed heart failure [PDF]

open access: yes, 2004
ObjectivesThe purpose of this research was to evaluate the therapeutic value of initiating a beta-blocker before an angiotensin-converting enzyme inhibitor (ACEI) in the treatment of heart failure.BackgroundAlthough ACEI and carvedilol produce benefits ...
Candy, Geoffrey   +8 more
core   +1 more source

Impact of Variability in Blood Pressure and Heart Rate on Beta‐Blocker Adherence

open access: yesThe Journal of Clinical Hypertension, Volume 27, Issue 5, May 2025.
ABSTRACT Adherence to antihypertensive medications is essential for blood pressure (BP) control, influencing long‐term outcomes in hypertensive patients. This study examines the association between visit‐to‐visit variability in BP and heart rate (HR) and its effect on adherence to beta‐blocker therapy among outpatients.
Yan Li   +9 more
wiley   +1 more source

Sevoflurane, Propofol and Carvedilol Block Myocardial Protection by Limb Remote Ischemic Preconditioning

open access: yesInternational Journal of Molecular Sciences, 2019
The effects of remote ischemic preconditioning (RIPC) in cardiac surgery have been inconsistent. We investigated whether anesthesia or beta-blockers interfere with RIPC cardioprotection.
Y. Cho   +6 more
semanticscholar   +1 more source

Nano and Microparticulate Chitosan Based System for Formulation of Carvedilol Rapid Melt Tablet

open access: yesAdvanced Pharmaceutical Bulletin, 2015
Purpose: In the present study rapid melt tablets (RMT’s) of carvedilol were prepared by using ionotropic-gelated chitosan nanoparticles using a spray-drying method.
Ravindra Patil   +2 more
doaj   +1 more source

Pepducins as a potential treatment strategy for asthma and COPD. [PDF]

open access: yes, 2018
Current therapies to treat asthma and other airway diseases primarily include anti-inflammatory agents and bronchodilators. Anti-inflammatory agents target trafficking and resident immunocytes and structural cells, while bronchodilators act to prevent or
Benovic, Jeffrey L.   +4 more
core   +2 more sources

Prognostic Role of Endoscopic Ultrasound Guided Direct Portal Pressure Gradient Measurement in Porto‐Sinusoidal Vascular Disorder

open access: yesLiver International, Volume 45, Issue 5, May 2025.
ABSTRACT Background & Aims HVPG is the gold standard for the diagnosis of clinically significant portal hypertension (CSPH), a condition associated with the risk of developing hepatic decompensation events. However, HVPG is an indirect method to measure portal pressure, and its application in the pre‐sinusoidal form of portal hypertension (PH), as in ...
Francesco Santopaolo   +12 more
wiley   +1 more source

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