Results 111 to 120 of about 2,031,294 (377)

Sediment Transport Management Using the Planned Construction of the Lower Vistula Cascade as an Example [PDF]

, 2022
Jarosław Biegowski, Małgorzata Robakiewicz, Krzysztof Woś, Krzysztof Wrzosek   +3 more
openalex   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Biomimetic enzyme cascade reaction system in microfluidic electrospray microcapsules

Science Advances, 2018
Biomimetic enzyme cascade reaction systems in microcapsules are developed for mimicking biocatalysis of organelles. Mimicking subcellular compartments containing enzymes in organisms is considered a promising approach to substitute for missing or lost ...
Huan Wang, Ze Zhao, Yuxiao Liu, C. Shao, Feika Bian, Yuanjin Zhao   +5 more
semanticscholar   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Identifying mothers and fathers of children in care using linked administrative data

International Journal of Population Data Science
Objectives There are challenges carrying out administrative data research on parents of children in the care system, particularly fathers, because of difficulties in linkage.
Nell Warner
doaj   +1 more source

Comparative analysis of sizing procedure for cooling and water heating cascade heat pump applied to a residential building

, 2023
Beomjun Kim, Su-Young Jo, Jae‐Weon Jeong   +2 more
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Transitions from child and adolescent mental health services (CAMHS) for young people with social care needs in Wales

International Journal of Population Data Science
Childhood to adulthood transitions are often characterised by instability and increased support needs, particularly for young people involved with mental health and social care services.
Louisa M Roberts
doaj   +1 more source

Integrating Two-Stage Phase Change Material Thermal Storage for Cascaded Waste Heat Recovery of Diesel-Engine-Powered Distributed Generation Systems: A Case Study

Energies, 2019
Thermal energy storage using the latent heat of phase change materials (PCMs) is a promising technique to solve the time mismatch between the availability and usage of flue gas heat in distributed generation systems (DGSs).
Dacheng Li, Yulong Ding, Peilun Wang, Shuhao Wang, Hua Yao, Jihong Wang, Yun Huang   +6 more
doaj   +1 more source

Enzymatic Cascade Reactions in Biosynthesis.

Angewandte Chemie, 2019
Enzyme-mediated cascade reactions are widespread in biosynthesis. To facilitate comparison with the mechanistic categorizations of cascade reactions by synthetic chemists and delineate the common underlying chemistry, we discuss four types of enzymatic ...
C. Walsh, B. Moore
semanticscholar   +1 more source