Results 81 to 90 of about 508,384 (268)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Modeling, Altitude Control, and Trajectory Planning of a Weather Balloon Subject to Wind Disturbances

Aerospace
Weather balloons are a popular tool to obtain atmospheric data. One of the biggest advantages of using this type of vehicle for scientific research is their inexpensiveness, as they are only composed of an inflated envelope, a parachute, and a sonde ...
Bruno Cândido, Catarina Rodrigues, Alexandra Moutinho, José Raul Azinheira   +3 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Comparative Real-Time Study of Three Enhanced Control Strategies Applied to Dynamic Process Systems

Applied Sciences
In this study, a comparative analysis of three different control methods for precise, real-time control of a complex dynamic double-tank liquid level process system was performed.
Kagan Koray Ayten, Ahmet Dumlu, Sadrettin Golcugezli, Emre Tusik, Gurkan Kalınay   +4 more
doaj   +1 more source

Extraction-controlled quantum cascade lasers [PDF]

Applied Physics Letters, 2010
A simple two-well design for terahertz quantum cascade lasers is proposed which is based on scattering injection and the efficient extraction of electrons from the lower laser level by resonant tunneling. In contrast to existing designs this extraction also controls the positive differential conductivity. The device is analyzed by calculations based on
openaire   +3 more sources

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Dual-Layer LAMDA-Based Cascade Control for Cooperative Formation of Aerial Manipulators

Actuators
This paper proposes a novel dual-layer learning-based cascade architecture, termed LAMDA-LAMDA, for cooperative formation control of aerial manipulators.
Gabriela M. Andaluz, Luis Morales, Paulo Leica, Guillermo Palacios-Navarro   +3 more
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Optimization of bidding strategy for leasing energy storage of wind farm clusters considering frequency regulation performance

Zhejiang dianli
Wind farm clusters can enhance their operational profitability while supporting grid frequency regulation by participating in frequency regulation markets through the leasing of energy storage. To achieve this， a game-theoretic optimization bidding model
LI Xianshan, HU Changyu, LI Ting, LI Wen, WEI Jie, WANG Shilong   +5 more
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source