Results 71 to 80 of about 508,384 (268)

Application of AFFDE-RBF-PID-PI Cascade Control in Heating Furnace Temperature Control System

open access: yesJournal of Applied Science and Engineering
Given the large hysteresis in the material outlet temperature of the heating furnace, a differential evolution algorithm with adaptive adjustment factors (AAFDE)-radial basis function (RBF)-proportional integral derivative (PID)-PI cascade is proposed ...
Yue-Ting Liu, Yan Zhang
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

Cascade Proportional–Integral Control Design and Affordable Instrumentation System for Enhanced Performance of Electrolytic Dry Cells

open access: yesSensors
In this paper, we present a cost-effective system for monitoring and controlling alkaline electrolyzers, intending to improve hydrogen gas production on a laboratory scale. Our work includes two main innovations.
Saulo N. Matos   +5 more
doaj   +1 more source

A Novel Predictable Rock Breaker Using Intelligent Hydraulic Control with ICT Convergences

open access: yesApplied Sciences, 2019
In this paper, a hydraulic breaker system is suggested with optimized impact forces and with active control to improve the system’s energy efficiency.
Bok-Joong Yoon, Kil-Soo Lee, Jae-Hak Lee
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Third-order harmonic currents suppression method based on selective component compensation for cascaded H-bridge STATCOM under asymmetric grid

open access: yesThe Journal of Engineering, 2019
To achieve low cost and compactness, small dc capacitance in dc-link is preferred in the cascaded H-bridge (CHB) static synchronous compensator (STATCOM).
Daorong Lu, Haibing Hu
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

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