Results 51 to 60 of about 508,384 (268)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Enhancing Operational Reliability in Industrial PTA Oxidation Reactors Using a Robust Cascade Control Scheme

open access: yesChemEngineering
Maintaining stable pressure in the oxidation–compressor section of purified terephthalic acid (PTA) plants is essential for ensuring efficient and reliable operation.
Andri Kapuji Kaharian   +3 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

The Neural Cascade of Attentional Control

open access: yesPLOS Biology, 2007
In our complex and multifaceted world, our senses are continuously bombarded with much more information than our brains can fully process. Attention is a critical cognitive function that allows us to select for detailed analysis only the most relevant information at any given moment. The crucial nature of attention is clearly evident in the game “Where'
openaire   +4 more sources

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Novel design method for cascade control structure of electric drives: Closed‐form expressions for control gains via pole placement

open access: yesIET Control Theory & Applications
Cascade control structures with inner current and outer speed loop, usually utilizing PI controllers, are widely used for electrical drives to meet high‐quality requirements. The present paper introduces design guidelines via pole placement for achieving
Csaba Budai   +2 more
doaj   +1 more source

Cooperative Control for Multi-Module Charging Systems of Ultracapacitors

open access: yesEnergies, 2020
Ultracapacitors have recently received great attention for energy storage due to their small pollution, high power density, and long lifetime. In many applications, ultracapacitors need to be charged with a high current, where a multi-module charging ...
Xiaoyong Zhang   +4 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Controlling the cascade of corona

open access: yesOpen Science Journal, 2020
The pandemic of the 2019 novel Coronavirus has seen unprecedented exponential growth. Within three months, 192 countries have been affected, crossing more than 1 million confirmed cases and over 60 thousand deaths until the first week of April. Decision making in such a pandemic becomes difficult due to limited data on the nature of the disease and its
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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