Results 111 to 120 of about 240,463 (263)

Parity‐Dependent THz Harmonic Generation in Electrically Pumped Micro‐Lasers Exploiting Topological Insulator–Metamaterial Gratings

Advanced Materials, EarlyView.
Topological insulator–metamaterials integrated with electrically driven terahertz quantum cascade lasers enable parity‐dependent harmonic generation. Bulk‐dominated Bi2Se3 favors third‐harmonic emission at 9.96 THz, whereas topological‐surface‐state‐dominated Bi2Se3, Bi2Te3, and (Bi,Sb)2Te3 generate strong second harmonics near 6.5 THz.
Alessandra Di Gaspare, Craig S. Knox, Ahmet Yagmur, Sara Ghayeb Zamharir, Lianhe Li, Satoshi Sasaki, A. Giles Davies, Edmund H. Linfield, Joshua R. Freeman, Miriam S. Vitiello   +9 more
wiley   +1 more source

Impact of stigma on the HIV care cascade among older persons living with HIV in sub-Saharan Africa: protocol for a systematic review

BMJ Open
Introduction Data are limited on the impact of stigma (stigma associated with HIV and/or stigma related to old age (ageism) or both) on linkage to the HIV care cascade among older persons (aged 50 years and older) in sub-Saharan Africa (SSA).
Moses Kamya, Anne Katahoire, Alison Annet Kinengyere, Moses Ocan, Joanita Nangendo, Fred C Semitala, Stephen Ojiambo Wandera, Laura Bogart   +7 more
doaj   +1 more source

Assessing inequities in buprenorphine treatment across the care cascade

Drug and Alcohol Dependence
Describe buprenorphine treatment gaps across the care cascade by race, ethnicity, age, sex and key clinical characteristics.Observational cohort study of new opioid use disorder (OUD) treatment episodes, 1/1/15-12/31/21 PARTICIPANTS: Individuals 16-89 years at Boston Medical Center and affiliated Boston-area clinics with OUD or buprenorphine ...
Alyssa S. Tilhou, Sarah Gasman, Jiayi Wang, Katherine Standish, Laura F. White, Ally Cogan, Morgan Devlin, Marc Larochelle, William G. Adams   +8 more
openaire   +3 more sources

Advances in Bio‐Integrated Edge Computing Systems for Smart and Connected Health

Advanced Materials, EarlyView.
This review explores advances in bio‐integrated edge computing for healthcare, focusing on co‐designing computing, sensing, and energy strategies to overcome integration and power challenges for optimized, decentralized operation. ABSTRACT Recent advances in bio‐integrated healthcare technologies have enabled continuous, high‐resolution monitoring and ...
Gyuwon Kim, Seungwon Yoo, Tae Woog Kang, Yunuo Huang, Woon‐Hong Yeo   +4 more
wiley   +1 more source

GaSex Nanoparticles Modulate Neutrophil Function and Mitigate NET‐Driven Osteogenic Impairment in Osteomyelitis Therapy

Advanced Materials, EarlyView.
Neutrophil extracellular traps (NETs) emerge as a critical repair‐limiting factor in osteomyelitis, driving osteoblast mitochondrial dysfunction and excessive PINK1/Parkin‐mediated mitophagy. Gallium–selenium nanoparticles (GaSex) scavenge reactive oxygen species, redirect neutrophils from NETosis toward bactericidal phagocytosis, eliminate methicillin‐
Kai Ye, Xuanzhe Liu, Zifan Pei, Chenyi Jiang, Xiaofen Zhang, Lin Lin, Qihang Fang, Binyu Chen, Longxiang Shen, Liang Cheng, Peng Ding, Xianyou Zheng   +11 more
wiley   +1 more source

A Retinal Matrix Stiffening Model Reveals FAK‐Dependent Mechanotransduction in Pericytes Underlies Vascular Destabilization

Advanced Materials, EarlyView.
In this study, we show that retinal matrix stiffness is increased in diabetic mice. Using engineered human vascular models with controlled matrix stiffness, we demonstrate that stiffening activates focal adhesion kinase (FAK) signaling in pericytes, suppresses Notch signaling, and disrupts vascular morphology.
Emily Warren, Alex Wu, Lucas Ramirez, Yaqing Huang, Connor Amelung, Sophia Saxonhouse, Sharon Gerecht   +6 more
wiley   +1 more source

A Coaxial Bioprinted Hydrogel With Semipermeable Sheath and Pro‐Chondrogenic Core for Articular Cartilage Repair

Advanced Materials, EarlyView.
A sheath‐core biomimetic hydrogel is engineered with a compartmentalized yet integrated architecture for synergistic multifunctionality. Its stiff, semipermeable sheath mimics the ECM's load‐bearing and protective roles, encapsulating a soft core that provides a pro‐chondrogenic microenvironment similar to the PCM.
Zheyuan Shi, Hua Zhang, Jingying Hu, Guanrong Li, Dianqing Wang, Cuicui Su, Gordon G. Wallace, Qi Gu, Jun Chen, Yingchun Zhu   +9 more
wiley   +1 more source

Effect of Nitrogen Doping on the Proton‐Irradiation Stability of Carbon Nanowalls

Advanced Materials Interfaces, EarlyView.
Proton irradiation effects in carbon nanowalls are systematically compared with nitrogen‐doped counterparts over a wide fluence range. While both systems maintain structural integrity, nitrogen incorporation alters the functional response under irradiation.
Baglan A. Kyrykbay, Rakhymzhan Ye. Zhumadilov, Renata R. Nemkayeva, Bauyrzhan Ye. Zhumadilov, Gulnur Akhtanova, Hryhorii Parkhomenko, Alexander V. Kireyev, Sagi A. Orazbayev, Tlekkabul S. Ramazanov, Maratbek T. Gabdullin, Askhat N. Jumabekov, Viktor V. Brus, Yerassyl Yerlanuly   +12 more
wiley   +1 more source

A Critical Review on the Evolution of Chitosan‐Based Injectable Hydrogels in Bone Regeneration

Advanced Materials Interfaces, EarlyView.
The graphical illustration depicts hydrogel formulation using chitosan and biocompatible cross‐linkers, major advantages, and incorporation of cells, osteoinductive factors, and therapeutic drugs. Following injection, pH‐responsive gelation enables controlled drug release, promotes cell recruitment and osteogenic differentiation, enhances extracellular
Shivani Santosh Sakhrani, Abu ul Hassan S. Rana, S. Sudheer Khan   +2 more
wiley   +1 more source

Implementing a primary-tertiary shared care model for enhancing cascade testing for familial hypercholesterolaemia: an effectiveness–implementation hybrid type III pre–post study

Implementation Science Communications
Background Familial hypercholesterolaemia (FH) is a common but underdiagnosed genetic condition that leads to high low-density lipoprotein cholesterol and premature cardiovascular disease.
Mitchell Sarkies, Madeline Calder, David Sullivan, Shubha Srinivasan, Catherine Spinks, Emile Belramoul, Ronald J. Trent, Claire Trumble, Charlotte Hespe, Stephen C. H. Li, Luke Elias, Brendan Goodger, Karen Birkenhead   +12 more
doaj   +1 more source