Results 211 to 220 of about 240,463 (263)

Nickel‐Catalyzed Three‐Component Difluoroalkylation‐Amination for the Direct Access to Anti‐Inflammatory β‐Difluoroalkyl Amines

Advanced Science, EarlyView.
A nickel‐catalyzed three‐component reductive fluoroalkylation‐amination strategy of N‐vinylamides for the direct access to the α‐amidyl‐β‐difluoroalkyl amines was reported here. The synthetic method features with broad substrate scope, mild conditions, high functional group tolerance, and convenience to handle.
Chang Xu, Fangting Ma, Fan Ding, Luyan Wang, Yunxi Li, Yunzhi He, Xingang Zhang, Siyu He, Dandan Liu   +8 more
wiley   +1 more source

Modeling the HIV Cascade of Care Using Routinely Collected Clinical Data to Guide Programmatic Interventions and Policy Decisions. [PDF]

J Acquir Immune Defic Syndr
Bakoyannis G, Elul B, Wools-Kaloustian KK, Brown S, Semeere A, Castelnuovo B, Diero L, Nakigozi G, Lyamuya R, Yiannoutsos CT, East Africa IeDEA Regional Consortium.   +10 more
europepmc   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Genotyped cluster investigations versus standard contact tracing: comparative impact on latent tuberculosis infection cascade of care in a low-incidence region. [PDF]

BMC Infect Dis
Asare-Baah M, Séraphin MN, Salmon-Trejo LAT, Johnston L, Dominique L, Ashkin D, Vaddiparti K, Kwara A, Maurelli AT, Lauzardo M.   +9 more
europepmc   +1 more source

Machine Learning‐Driven Design of Multicomponent Bone Inorganic Matrix Mimicking Scaffolds for Osteogenesis Enhanced by Neurogenesis

Advanced Science, EarlyView.
Schematic illustration of development of experimental datasets and algorithm models, screening and preparation of the scaffolds and their applications in vivo. ABSTRACT Bone defects require materials with osteogenic, neurogenic, and angiogenic activity, yet designing such materials within high‐dimensional compositional spaces remains challenging. Here,
Kunlu Lin, Ying Yang, Chuyao Zhou, Hanyue Mao, Zhiquan Zhang, Libangxi Liu, Xiaoying Yu, Haoming Liu, Long Liu, Xiaoyan Wang   +9 more
wiley   +1 more source

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio‐Interactive Materials

Advanced Science, EarlyView.
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan, Fuming Cao, Junqiang Mao, Pengbin Yin, Licheng Zhang, Jianjun Wang, Peifu Tang   +6 more
wiley   +1 more source

Application of an opioid use disorder cascade of care in a large public health system. [PDF]

Am J Drug Alcohol Abuse
Carter E, Schatz D, Isaacs N, Garcia J, Henry B, Krawczyk N, Williams AR.   +6 more
europepmc   +1 more source

Evaluation of the New York City COVID-19 case investigation and contact tracing program: a cascade of care analysis. [PDF]

BMC Public Health
Conderino S, E Thorpe L, Shilpi Islam N, A Berry C, Bendik S, Massar R, Hong C, Fair A, Bershteyn A.   +8 more
europepmc   +1 more source

Hepatitis C Cascade of Care in a Multidisciplinary Substance Use Bridge Clinic Model in Tennessee. [PDF]

Open Forum Infect Dis
Chirunomula S, Muscarella A, Whelchel K, Gispen F, Marcovitz D, White K, Chastain C.   +6 more
europepmc   +1 more source

Cascade of care for hypertension among apparently healthy and unhealthy individuals of 25-64 years in the Czech Republic. [PDF]

PLoS One
Berka B, Lustigová M, Urbanová J, Krollová P, Hloch O, Romanová A, Michalec J, Taniwall A, Žejglicová K, Malinovská J, Jenšovský M, Vejtasová V, González-Rivas JP, Maranhao Neto GA, Pavlovska I, Brož J.   +15 more
europepmc   +1 more source