Results 71 to 80 of about 6,085 (289)

An Investigation into Cascading Failure in Large-Scale Electric Grids: A Load-Redistribution Approach

open access: yesApplied Sciences, 2018
In this study, we propose a load-redistribution-based practical cascading failure model that analyses the dynamic behaviour of a power system upon the occurrence of node failures.
Guidong Zhang   +5 more
doaj   +1 more source

A Probabilistic Cascading Failure Model for Dynamic Operating Conditions

open access: yesIEEE Access, 2020
Failure propagation in power systems, and the possibility of becoming a cascading event, depend significantly on power system operating conditions. To make informed operating decisions that aim at preventing cascading failures, it is crucial to know the ...
Rui Ma   +4 more
doaj   +1 more source

Cascading failure and robustness in metabolic networks [PDF]

open access: yesProceedings of the National Academy of Sciences, 2008
We investigate the relationship between structure and robustness in the metabolic networks of Escherichia coli , Methanosarcina barkeri , Staphylococcus aureus , and Saccharomyces cerevisiae , using a cascading failure model based on a ...
Ashley G, Smart   +2 more
openaire   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Catastrophic cascading failures in power networks

open access: yesTheoretical Computer Science, 2015
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Jungtaek Seo   +3 more
openaire   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Optimization of Water Distribution Network Design for Resisting Cascading Failures

open access: yesIEEE Access, 2020
Water distribution networks (WDNs) is crucial to ensure social operations and economic activities. However, WDNs are highly sensitive and vulnerable to disasters. The aim of this study is to mitigate the catastrophic consequences of cascading failures in
Qing Shuang, Chao Ran Huang, Jun Wang
doaj   +1 more source

Cascading failures in networks with proximate dependent nodes [PDF]

open access: yesPhysical Review E, 2014
We study the mutual percolation of a system composed of two interdependent random regular networks. We introduce a notion of distance to explore the effects of the proximity of interdependent nodes on the cascade of failures after an initial attack.
Yosef Kornbluth   +3 more
openaire   +3 more sources

Cascading Failures: Survival versus Prevention

open access: yes, 2003
While measures can be taken to reduce the number of large-scale power losses due to failures of the generation and high-voltage transmission grid, such failures cannot be eliminated. The survival of essential missions is a more tractable problem than the
Sarosh Talukdar (5355377)   +4 more
core   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

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