Results 51 to 60 of about 6,085 (289)

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Mechanism and path search method for Voltage-Dominated cascading failures in Power-Electronized power systems

International Journal of Electrical Power & Energy Systems
The strong coupling and controllable characteristics of power electronic equipment lead to the emergence of novel voltage-dominated cascading failures in power systems.
Jinxin Ouyang, Fei Huang, Shuqi Bi, Taiyu Xiao   +3 more
doaj   +1 more source

Cascading failures and maintenance optimization of urban transportation networks

, 2023
A convenient urban transportation network facilitates a high-quality life and a high-growth economy. Due to cascading failures being a ticklish question triggering continuous road congestion, the maintenance plan is momentous to restore the urban ...
Liwei Chen, Shaomin Wu, Chen, Liwei, Zhang, Yulu, Yulu Zhang, Wu, Shaomin, Dui, Hongyan, Hongyan Dui   +7 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Cascading failures in power grids

Proceedings of the 5th international conference on Future energy systems, 2014
This paper focuses on cascading line failures in the transmission system of the power grid. Recent large-scale power outages demonstrated the limitations of percolation- and epid- emic-based tools in modeling cascades. Hence, we study cascades by using computational tools and a linearized power flow model.
Saleh Soltan, Dorian Mazauric, Gil Zussman   +2 more
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Exploring cascading failure in directed weighted small-world network: An adaptive SIRS-F mechanism

International Journal of Electrical Power & Energy Systems
Cascading failures in complex networks is a significant threat to system reliability and robustness, influencing various aspects of daily life. The small-world characteristics within complex networks contribute to increased complexity, making it ...
Wenjie Tian, Jihui Xu, Chuhan Zhou, Lu Chen, Xingqi Zou   +4 more
doaj   +1 more source

Controllability Robustness Against Cascading Failure for Complex Logistic Network Based on Dynamic Cascading Failure Model [PDF]

IEEE Access, 2020
Inspired by the empirical dynamic characteristics of the load of real logistics network, we propose a dynamic cascading failure model against cascading failure, which is more suitable for complex logistics network by adding dynamic factors based on the nonlinear load-capacity model under initial residual capacity load-redistribution strategy.
Shaohua Wang 0006, Yue Yang 0029, Liyue Sun, Xiaoni Li, Yongxing Li, Konghui Guo   +5 more
openaire   +3 more sources

Data-Driven Distributionally Robust Mitigation of Risk of Cascading Failures

, 2023
We introduce a novel data-driven method to mitigate the risk of cascading failures in delayed discrete-time Linear Time-Invariant (LTI) systems. Our approach involves formulating a distributionally robust finite-horizon optimal control problem, where the
Motee, Nader, Pandey, Vivek, Amini, Arash, Liu, Guangyi   +3 more
core