Results 111 to 120 of about 3,245,764 (246)

The Limits of Case-Control Studies

Epidemiology, 2006
Andreas, Stang, Karl-Heinz, Jöckel
openaire   +3 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

A case⁃control study on psychosocial risk factors for mild cognitive impairment in elders

Chinese Journal of Contemporary Neurology and Neurosurgery, 2010
Objective To investigate the psychosocial risk factors for mild cognitive impairment (MCI) in old people. Methods A case⁃control study was conducted in MCI and normal cognition elders.
Fu⁃bin JIAO, Ji⁃ping TAN, Lu⁃ning WANG   +2 more
doaj  

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Associação entre fatores sócio-econômicos e mortalidade infantil por diarréia, pneumonia e desnutrição em região metropolitana do Sudeste do Brasil: um estudo caso-controle

Cadernos de Saúde Pública
Para investigar fatores determinantes da mortalidade infantil pós-neonatal por diarréia, pneumonia e desnutrição, abordadas como um mesmo grupamento de causas, realizou-se um estudo caso-controle de base populacional na Região Metropolitana de Belo ...
Elisabeth França, José Moreira de Souza, Mark Drew Crosland Guimarães, Eugênio Marcos Andrade Goulart, Enrico Colosimo, Carlos Maurício de Figueiredo Antunes   +5 more
doaj  

Collapsibility in case-control studies. [PDF]

Int J Epidemiol
Pearce N.
europepmc   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Use of causal inference methods in case-control studies: a methodology review. [PDF]

Am J Epidemiol
Mésidor M, Xu M, Diop A, Fantodji C, Parent MÉ, Keil A.   +5 more
europepmc   +1 more source