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Much medical research is observational. The reporting of observational studies is often of insufficient quality. Poor reporting hampers the assessment of the strengths and weaknesses of a study and the generalisability of its results. Taking into account
Jan P. Vandenbroucke +8 more
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When is a case-control study not a case-control study?
There is confusion in the rehabilitation literature about case-control studies because terms such as "cases" and "controls", used to refer to the subjects in the study, are confused with the design of the study. The aim of this study was to estimate the extent to which the label "case-control study" is misused in the rehabilitation literature and in ...
Nancy E, Mayo, Mark S, Goldberg
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Methodology series module 2: Case-control studies
Case-Control study design is a type of observational study. In this design, participants are selected for the study based on their outcome status. Thus, some participants have the outcome of interest (referred to as cases), whereas others do not have the
Maninder Singh Setia
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Research Design: Case-Control Studies
Case-control studies are observational studies in which cases are subjects who have a characteristic of interest, such as a clinical diagnosis, and controls are (usually) matched subjects who do not have that characteristic.
Chittaranjan Andrade
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When is a case-control study a case-control study?
Rehabilitation professionals rarely ask questions about the etiology of health events or outcomes and may not have formal training or relevant experience in the design of studies whose intent is to identify causal factors. The case-control study, which is one design used to answer questions about etiology, is particularly difficult to understand and ...
Nancy E, Mayo, Mark S, Goldberg
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Sample Size and Statistical Power Calculation in Genetic Association Studies [PDF]
A sample size with sufficient statistical power is critical to the success of genetic association studies to detect causal genes of human complex diseases.
Eun Pyo Hong, Ji Wan Park
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Effects of antibiotic consumption on children 2-8 years of age developing asthma [PDF]
OBJECTIVES Antibiotic exposure in children is a possible contributor to the increasing asthma prevalence in several countries. The present study aimed to investigate the association between antibiotic exposure and the risk of developing childhood asthma ...
Hamid Reza Khalkhali +5 more
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Background In May 2015, a cholera outbreak that had lasted 3 months and infected over 100 people was reported in Kasese District, Uganda, where multiple cholera outbreaks had occurred previously.
Benon Kwesiga +5 more
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ABSTRACT Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...
Michael Abele +19 more
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ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source

