Results 71 to 80 of about 2,124,166 (301)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Does counseling increase sustained benefit of HAART among prison inmates after release to the community? [PDF]
, 2005 The lack of sustained effectiveness of HAART after release to the community of HIV-infected inmates treated in prison was well demonstrated by Springer et al. in a recent article.
Babudieri, Sergio +4 more
core +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Community health workers and stand-alone or integrated case management of malaria: a systematic literature review. [PDF]
, 2014 A systematic literature review was conducted to assess the effectiveness of strategies to improve community case management (CCM) of malaria. Forty-three studies were included; most (38) reported indicators of community health worker (CHW) performance ...
Buj, Valentina +8 more
core +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Working Within a Perfect Storm: The Current UK Care Crisis in Community Neurorehabilitation
Journal of Long-Term CareContext: Within the UK, there is a shortage of support workers required to meet the needs of individuals with acquired brain injuries who often require extensive care packages.
Alyson Norman +8 more
doaj +1 more source
Does case management improve outcomes for people with schizophrenia? [PDF]
The Australian and New Zealand clinical practice guidelines recommend intensive case management for people with first-episode psychosis or an acute relapse of schizophrenia.
Alana Shepherd +4 more
core
Case management of persons with acquired immunodeficiency syndrome in San Francisco. [PDF]
, 1988 The acquired immunodeficiency syndrome (AIDS) epidemic represents a growing challenge for the health care system and for case management models applied to persons with AIDS.
Benjamin, AR, Lee, PR, Solkowitz, SN
core
Outcomes For Street Children and Youth Under Multidisciplinary Care in a Drop-In Centre in Tegucigalpa, Honduras [PDF]
, 2010 BACKGROUND: There is little evidence to describe the feasibility and outcomes of services for the care of street children and youth in low-income countries.
Briceño-Leon R. +7 more
core +2 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source