Results 61 to 70 of about 16,227,119 (247)

Reporting epidemics: newspapers, information dissemination and the story of Ebola in the Ugandan district of Luweero

open access: yesThe Pan African Medical Journal, 2011
When an outbreak occurs, the affected population needs timely information in order to make informed decisions on how best to deal with the situation. Most target populations rely on the media for their information and the authorities use the media to ...
Allan Mwesiga
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Jmenná deklinace v altajských jazycích

open access: yesLinguistica Brunensia, 2014
In the article the nominal declension in five branches of Altaic languages is summarized, reconstructed in daughter protolanguages and these case protosystems are compared to obtain the hypothetical Altaic case protosystem.
Václav Blažek, Michal Schwarz
doaj  

THE CONCEPTS OF THE SIMPLEST AND SIMPLE SENTENCES IN THE PARADIGM OF SYSTEMIC THEORY OF CASE

open access: yesRUDN Journal of Language Studies, Semiotics and Semantics, 2019
The article presents some of the results of systematic studies of the functions of the cases in a simple Russian sentence. Primarily, the systemic interpretation of the simplest and simple sentences as syntactic units is postulated, which possess not ...
Alexey F Dremov
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Müşteri Memnuniyetinin Sağlanmasında Hataların Önlenmesine Yönelik Üretim Odaklı Bir Bakış Açısı: Poka-Yoke Sistemleri

open access: yesSelçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2014
Günümüz küresel rekabet ortamında işletmelerin kullandıklarımodern teknolojik altyapıya sahip ileri imalat sistemlerinde bile çeşitli nedenlerle bir takım sorunlar meydana gelebilmektedir.
Muammer Zerenler, Kazım Karaboğa
doaj  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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