Results 81 to 90 of about 13,315,758 (295)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
African American Scholars at Case
African American Scholars at Case is a digital initiative that focuses on the presence of African Americans at Case Western Reserve University since its inception.
Johnson, Gwendolyn G. (Creatorcre) +1 more
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Application of Operations Research in Research Planning - A Case Study
Operations Research ...
Johnson, E. (Creatorcre)
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Operations Research Reports. Statement on Potentially Harmful Content: Digital Case provides access to historical and primary sources that may include language or content that is outdated, biased, offensive, or harmful.
Agnew, Malcolm J. (Creatorcre) +1 more
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The dossier 'Smako Skrijelj': The contribution to the study of the State Security Administration work in the area of Tutin and surrounding after the Second World War [PDF]
Baština, 2012 The activity of the Yugoslav Security Service due to its importance for the preservation of the newly established social set up, and evident controversies accompanying its work, attracts the attention of professional public opinion.
Živković Milutin
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