Results 221 to 230 of about 10,535,187 (345)

Associated Autoimmunity in Myasthenia Gravis in Denmark: A Nationwide Case-Control Study. [PDF]

Eur J Neurol
Nielsen JJJ, Levison LS, Andersen H.
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Correction to: Determinants of chemotherapy abandonment in Ethiopia: a nested case-control study. [PDF]

Oncologist
europepmc   +1 more source

Association between periodontitis, leukoaraiosis and sTWEAK. A case-control study. [PDF]

Front Oral Health
Moldes J, Arnau A, Rodríguez-Yáñez M, López-Dequidt I, Hervella P, Blanco J, Iglesias-Rey R, Sobrino T, Leira Y.   +8 more
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Mandibular Movement During Swallowing in Patients with Tinnitus: An Instrumented Case-Control Study. [PDF]

Audiol Res
Didier HA, Di Berardino F, Lilli G, Zanetti D, Didier AH, Raponi G, Leone SJ, Romano S, Farronato M, Boccalari E, Serafin M, Caprioglio A, Re D, Giannì AB.   +13 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Sociodemographic and Clinical Determinants of Glaucoma in a Sub-Saharan African Population: A Case-Control Study. [PDF]

Health Sci Rep
Ampong A, Lartey S, Tagoe NN, Essuman YA, Abaidoo B, Beyuo VM, Owusu-Asare LP, Ofori-Adjei DI, Essuman VA.   +8 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Cytokines and adolescent anorexia nervosa: a case-control study. [PDF]

BMC Psychiatry
Ferencova N, Visnovcova Z, Ondrejka I, Hrtanek I, Funakova D, Tonhajzerova I.   +5 more
europepmc   +1 more source