Results 231 to 240 of about 10,535,187 (345)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Clinicopathological and Prognostic Characteristics of Gastric-Type Endocervical Adenocarcinoma: A Nested Case-Control Study. [PDF]

Cancers (Basel)
Liu Y, Hu Y, Wang H, Qiu L, Sun X, Yin X, Luo S, Yin Y, Cong Q, Tao X, Ning Y, Zhao Y, Liu H, Jiang H, Lin X, Wu X.   +15 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Clinical and Radiographic Factors Associated With Rotator Cuff Tears: A Case-Control Study. [PDF]

Cureus
Masmoudi Z, Masmoudi S, Khlif MA, Zitouna K, Riahi H, Barsaoui M.   +5 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

miRNA-Processing Gene Variants and Neuroblastoma Susceptibility: A Pilot Case-Control Study. [PDF]

Cureus
Kyriakidis I, Pelagiadis I, Martimianaki G, Stratigaki M, Katzilakis N, Stiakaki E.   +5 more
europepmc   +1 more source

Case Study on Residential Humidity Control at U.S. Coast Guard Bayamon Housing

, 2004
Ivan R. Meneses
openalex   +1 more source

HIF1A gene Pro582Ser polymorphism and susceptibility to digestive tract cancers: a meta-analysis of case-control studies

, 2014
Jinjiang Xu, Lihui Xu, L.T. Li, Qian You, Lijun Cha   +4 more
openalex   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Predictive value of fibrinogen-to-albumin ratio in early missed miscarriage: a case-control study. [PDF]

Front Med (Lausanne)
Liu W, Tang S, Deng M.
europepmc   +1 more source