We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Practical challenges regarding the application of infringement procedures to protect judicial independence and the rule of law in EU member states [PDF]
This article examines the role of infringement procedures in safeguarding judicial independence and the Rule of Law in European Union Member States. The study analyzes the legal framework, relevant case law of the Court of Justice of the European Union ...
Oganesean Armen
doaj +1 more source
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
GUARANTEEING THE ACCES OF THIRD PARTIES TO THE NETWORK INDUSTRIES SPECIFIC INFRASTRUCTURES – A VITAL COMPONENT OF EU'S POLICY IN THE FIELD OF COMPETITION ON THE ENERGY MARKET, IN THE CONTEXT OF THE NEED TO INSURE ENERGY INDEPENDENCE WHILE MANTAINING AFFORDABLE PRICES [PDF]
As both the practical experience and the theoretical constructions of successive generations of practitioners and researchers of the phenomenon of the economy and the legal norms associated with its proper functioning have proven, the most important ...
Iulian BĂICULESCU +1 more
doaj
(Un)Conditional Welfare? Tensions Between Welfare Rights and Migration Control in Swiss Case Law
This analysis of Swiss Federal Supreme Court judgements shows the coupling of welfare and migration control. Foreign nationals depending on social assistance might face the withdrawal of their residence permits.
Borrelli Lisa Marie +3 more
doaj +1 more source
Adjudication Problems of the National Appeals Chamber
The article is of a scientific and research nature and presents concisely the problems related with the case law of the National Appeals Chamber (Pol. Krajowa Izba Odwoławcza).
Małgorzata Rakowska
doaj +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
In recent years a discernible political trend has developed, particularly in Europe and the United States, towards phasing out or at least significantly reducing the use and harm of animals in research.
Nicole Lüthi +2 more
doaj +1 more source
Set-off as a way of ending obligations [PDF]
In this work the authors analyzed set-off as one of the most common and most significant way of ending obligations in our legal system. The most important and in practice the most common way of ending obligations is their fulfillment.
Radovanov Aleksandar, Danojlić Miladin
doaj
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source

