Results 61 to 70 of about 8,148,710 (302)

Gamified budgeting for managing household finances [PDF]

open access: yes, 2017
The current UK economic climate is leading households into debt. The rising cost of living and inflation are resulting in households struggling with financial management. This has implications on the quality of life and economic mobility.
Butt , Prins, Sievenpiper , Michael
core  

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Institutions as Objects in Fourth Order Design

open access: yesShe Ji: The Journal of Design, Economics and Innovation
Fourth order design, which involves systems and environments, is a frequently misunderstood area of design. The concept of institution offers a way to clarify and enrich fourth order design in both theory and practice.
Kipum Lee
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The concrete structure remedial assessements in marine environment from whole life asset management perspectives [PDF]

open access: yes, 2008
This study makes use of a desk top review methodology to discover and understand the remedial assessment of damage concrete structures in the marine environment (sea water). Basically, the restorations of asset marine facility are done by using a correct
Mohd Salleh, Mohd Rezal
core  

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Preclinical obesity curriculum: audit, implementation, and evaluation

open access: yesBMC Medical Education
Background This study aimed to (1) evaluate the current status of obesity education at Case Western Reserve University School of Medicine (CWRU) (2), introduce a comprehensive first-year curriculum on obesity, and (3) assess the impact of the curriculum ...
Amber Olson   +5 more
doaj   +1 more source

University of Cambridge - Case study in funding research data management [PDF]

open access: yes, 2018
This case study was written by Mary Donaldson as part of the Funder Requirements for Research Data project. This project was funded by JISC as part of the wider Research Data Management Business Case and Costings (RDM-BCC) project.
Donaldson, Mary
core   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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