Results 161 to 170 of about 9,172,312 (306)

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Analysis of the Reserve Book System at the Health Center Library

Operations Research ...
Mehta, Shailesh (Creatorcre), Darukhanavala, Phiroz P. (Creatorcre), Shroff, Pradip H. (Creatorcre), Dadachanji, Keki R. (Creatorcre)   +3 more
core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Radiofrequency Identification Marker-Guided Right S7 Segmentectomy for a Deeply Located Pulmonary Nodule: A Case Report. [PDF]

Surg Case Rep
Matsubara T, Kinoshita F, Iwamoto N, Takada K, Takenaka T, Yoshizumi T.   +5 more
europepmc   +1 more source

The Association of Individual Characteristics with Success and Failure of U. S. Army Recruiters

Operations Research ...
Coleman, F. David (Creatorcre)
core  

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Stepwise diagnosis and minimally invasive management of obscure gastrointestinal bleeding secondary to a Meckel's diverticulum: a case report. [PDF]

J Med Case Rep
He J, Liu W, Tong L, Yang H, Li G, Chen L, Liao Y.   +6 more
europepmc   +1 more source

An Annotated Bibliography: Applications of Operations research to Educational Systems

Operations Research ...
Balinsky, Warren (Creatorcre)
core  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

The Accuracy in Estimating Truck Class Rates for Logistical Planning

Operations Research ...
Ballou, Ronald (Creatorcre)
core