Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Management of Scapular Osteochondroma: An Uncommon Report of Two Cases. [PDF]
Sharma P, Chowdhury A, Rustagi A.
europepmc +1 more source
Applications of Multi-Attribute Utility Theory in the Health Care Delivery System Since 1970
Operations Research ...
Reisman, Arnold (Creatorcre) +1 more
core
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Refining Knee Radiofrequency Ablation with a Palisade- Guided Technique: A Case Report. [PDF]
Anashev T +3 more
europepmc +1 more source
Analysis of Feedback Models of Higher Education Degree Production
Operations Research ...
Michenzi, Alfred R. (Creatorcre)
core
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Case of unilateral biportal endoscopic management of multilevel thoracic spinal epidural abscess with acute paraplegia. [PDF]
Guerrero-Pérez R +5 more
europepmc +1 more source
Anesthesiology Manpower Planning Study Phase III - Final Report
Operations Research ...
Reisman, A. (Creatorcre) +9 more
core
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source

