Results 181 to 190 of about 34,369,254 (402)

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

ARSENIURETED HYDROGEN POISONING.WITH REPORT OF FIVE CASES. [PDF]

, 1907
Noble Wiley Jones
openalex   +1 more source

Degenerative Scoliosis: a Case Report [PDF]

, 2019
Background: Scoliosis in adults is a spinal deformity in adult patients with a Cobb angle of more than 10° in the coronal plane. Degenerative scoliosis is a term used for the presence of spinal coronal deviation in the elderly population due to segment ...
Alaydrus, M. M. (M), Martiana, I. K. (I)
core  

The SCARE 2018 statement: Updating consensus Surgical CAse REport (SCARE) guidelines.

International Journal of Surgery, 2018
R. Agha, M. Borrelli, R. Farwana, K. Koshy, A. Fowler, D. Orgill, Hongyi Zhu, A. Alsawadi, A. Noureldin, A. Rao, A. Enam, A.M.T. ThomÃ, M. Bashashati, Baskaran Vasudevan, A. Beamish, B. Challacombe, R. D. de Wilde, D. Machado-Aranda, D. Laskin, D. Muzumdar, A. D'cruz, T. Manning, D. Healy, D. Pagano, P. Goel, P. Ranganathan, P. Pai, S. Raja, M. Ather, Hüseyin kadioäžlu, I. Nixon, I. Mukherjee, J. Gómez Rivas, K. Raveendran, L. Derbyshire, Michele Valmasoni, Mushtaq Chalkoo, N. Raison, O. Muensterer, Patrick Bradley, R. Coppola, R. Afifi, D. Rosin, Roberto Klappenbach, R. Wynn, S. Giordano, S. Basu, S. Surani, Paritosh Suman, M. Thorat, V. Kasi   +50 more
semanticscholar   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

MULTIPLE SCLEROSIS, WITH A REPORT OF TWO ADDITIONAL CASES, WITH NECROPSY [PDF]

, 1904
WILLIAM G. SPILLER, C D Camp
openalex   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Leukemia and Exposure to X-Ray: A Report of 6 Cases

, 1959
William C. Moloney
openalex   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

Molecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla, Simone Venz, Ruslan Al‐Ali, Martin Wendlandt, Mandy Radefeldt, Elke Krüger   +5 more
wiley   +1 more source

MACROGENITOSOMIA PRECOX ASSOCIATED WITH HYPERPLASIA OF THE ANDROGENIC TISSUE OF THE ADRENAL AND DEATH FROM CORTICOADRENAL INSUFFICIENCY CASE REPORT¹

, 1940
Lawson Wilkins, Walter Fleischmann, John Eager Howard   +2 more
openalex   +1 more source