Results 141 to 150 of about 20,150,065 (344)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Joint effects of prenatal household air pollution exposure from multiple sources on preterm birth - A case-control study with propensity score matching [PDF]

open access: green, 2022
Xin-Chen Liu   +9 more
openalex   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Étude de Cas Sur le Développement de la Publication Leaders—Guide du Superviseur

open access: yesDiscourse and Writing/Rédactologie, 1986
Stewart Malcolm
doaj   +1 more source

STUDI KASUS PENERAPAN PENDEKATAN SAINTIFIK PADA GURU-GURU DI SMA N 1 BAWANG (STUDI PADA TAHUN AJARAN 2013/2014)

open access: yesEconomic Education Analysis Journal, 2014
Pendekatan saintifik adalah pendekatan yang digunakan dalam kurikulum 2013. Sebagian besar guru di SMA N 1 Bawang belum menerapkan pendekatan saintifik. Penelitian ini dilakukan di SMA N 1 Bawang Kabupaten Batang dengan menggunakan pendekatan kualitatif ...
Mei Fita Aryani
doaj  

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