Results 141 to 150 of about 91,991,955 (298)

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Algorithms for Discounted Stachastic Games

Operations Research ...
Nair, K. P. K. (Creatorcre), Rao, S. Subba (Creatorcre), Chandrasekaran, R. (Creatorcre)   +2 more
core  

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The Association of Individual Characteristics with Success and Failure of U. S. Army Recruiters

Operations Research ...
Coleman, F. David (Creatorcre)
core  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Contextualising English generalist day centres for older people: operational characteristics and typical days. Findings from case study research

, 2021
Orellana K, Manthorpe J, Tinker A.
europepmc   +1 more source

Examining 'institutional entrepreneurship' in healthcare redesign and improvement through comparative case study research: a study protocol. [PDF]

BMJ Open, 2018
Melder A, Burns P, Mcloughlin I, Teede H.   +3 more
europepmc   +1 more source

Analysis of the Reserve Book System at the Health Center Library

Operations Research ...
Mehta, Shailesh (Creatorcre), Darukhanavala, Phiroz P. (Creatorcre), Shroff, Pradip H. (Creatorcre), Dadachanji, Keki R. (Creatorcre)   +3 more
core  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

A gamified cognitive behavioral therapy for Arabs to reduce symptoms of depression and anxiety: A case study research. [PDF]

Digit Health
Amer NA, Shohieb SM, Eladrosy W, Liu S, Nam Y, Abdelrazek S.   +5 more
europepmc   +1 more source