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Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Passiv damping on spacecraft sandwich panels [PDF]
For reusable and expendable launch vehicles as well as for other spacecraft structural vibration loads are safety critical design drivers impacting mass and lifetime. Here, the improvement of reliability and safety, the reduction of mass, the extension
Panning, L. +3 more
core
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Casing deformation seriously restricts the development and utilization of shale gas in Baima block. To clarify the stress variation law of perforated casing under fault slip, study was conducted using a combination of field investigation and numerical ...
Qin Wenbin +5 more
doaj +1 more source
The existing research methods are inadequate to accurately characterize the actual casing-cement sheath failure.By combining numerical simulation with laboratory experiment,a test device was developed to measure the casing-cement sheath interface bond ...
Wang Yangang +5 more
doaj
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Casing deformation seriously affects the fracturing progress and stimulation effect of shale gas reservoirs. Considering casing deformations in fractured deep shale gas wells in the Luzhou block of southern Sichuan Basin, the influences of micro ...
Cheng Shen +4 more
doaj +1 more source
Casing deformation occurs frequently during the development of the Weirong Shale Gas Field in the Sichuan Basin.In order to solve this problem,analysis on load and deformation degree of three casing deformation has been carried out by finite element ...
QIAO Zhiguo, YE Cuilian
doaj
The frequent occurrence of casing failure has significantly affected the development of shale gas in the Sichuan Basin. Based on engineering and geology analyses, natural fracture/fault slip leads to casing shear deformation during hydraulic fracturing ...
Hu Meng +6 more
doaj +1 more source
NKCC1: A key regulator of glioblastoma progression
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source

