Results 61 to 70 of about 21,765 (305)

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

Analysis of Influence of Strata Dip Angle on Shear Deformation of Drilling Casing

Meikuang Anquan, 2020
Aiming at the shear failure of drilling casing, based on the movement law of overlying strata in coal seam mining, the finite element model of shear deformation of drilling casing is established by ANSYS numerical simulation software, and the effect of ...
ZHANG Qipeng, WEN Xiaojiang, TAN Dongsheng, CHEN Xinyi, YU Hui
doaj   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Deformation Law and Strength Evaluation Method of Casing in Puguang Gas Field

Shiyou jixie, 2019
To study the deformation law and residual strength evaluation method of P110SS casing applied in Puguang gas field, the material nonlinearity and geometric nonlinear model are used to establish the casing-cement sheath-formation finite element model ...
Yan Biao, Liu Fangjian, Wang Qingchao
doaj  

Snowboard, Ski, and Skateboard Sensor System Application [PDF]

, 2014
The goal of this project was develop a sensor for the commercial market for skiers, snowboarders, and skateboarders that can give them the data such as speed, elevation, pressure, temperature, flex, acceleration, position, and other performance data such
Doiron, Adrien, Fernandez, Michael, Ojeda, Victor, Ross, Robert   +3 more
core   +1 more source

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou, Marc Jaskir, Julian Gal, Yombe Fonkeu, Christos Davatzikos, MacLean P. Nasrallah, Jose Garcia, Stephen J. Bagley, Arati Desai, Richard E. Phillips, Steven Tobochnik, Colin A. Ellis, James J. Gugger, Nishant Sinha, Joel M. Stein, Kathryn A. Davis   +15 more
wiley   +1 more source

Deformation mechanism of horizontal shale gas well production casing and its engineering solution: A case study on the Huangjinba Block of the Zhaotong National Shale Gas Demonstration Zone

Natural Gas Industry B, 2018
In the Huangjinba Block of the Zhaotong National Shale Gas Demonstration Zone in the periphery of the Sichuan Basin, two horizontal shale gas wells suffer severe casing deformation.
Liuwei Li, Gaocheng Wang, Zhanghua Lian, Lei Zhang, Jue Mei, Yulou He   +5 more
doaj   +1 more source

Field investigation of deformation characteristics and stress mobilisation of a soil slope [PDF]

, 2015
Stress mobilisation and deformation of a slope are important for engineers to carry out reliable design of retaining systems. However, most case histories reported mainly on the response of pore-water pressure (PWP), whereas knowledge about the stress ...
AK Leung, AK Leung, AK Leung, Anthony Kwan Leung, BSI, Charles Wang Wai Ng, CWW Ng, CWW Ng, CWW Ng, CWW Ng, CWW Ng, I Meilani, IJA Brackley, JA Smethurst, JD Coleman, K Sassa, MT Genuchten Van, N Khalili, SMO, T Sakaki, TT Lim, WA Take, YK Kim   +22 more
core   +3 more sources

CASES OF OSTEOTOMY FOR RACHITIC DEFORMITY OF THE LEGS. [PDF]

The Lancet, 1877
n ...
openaire   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source