Results 91 to 100 of about 7,266 (305)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

A CASE OF ECLAMPSIA, WITH ALBUMINURIA; TREATMENT. [PDF]

open access: yesJournal of the American Medical Association, 1888
ABSTRACT Mrs. H., aet. 35, multipara, was taken with convulsions at end of eighth month of pregnancy. At 4 o'clock in the morning of September 28 her husband was aroused from sleep by the convulsive action and labored breathing of his wife. I was called immediately and found patient in a comatose state; face and hands and, in fact, the whole body ...
openaire   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Stall Margin Improvement by Casing Treatment—Its Mechanism and Effectiveness

open access: yes, 1977
Experiments on the effect of casing treatment were carried out using low-speed axial-flow compressors. Results on the overall compressor performance and on the flow through the blade row as well as the flow within the treatment slots are presented. Then,
H. Takata, Y. Tsukuda
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Flow Stability Model for Fan/Compressors with Annular Duct and Novel Casing Treatment

open access: yes, 2012
A three-dimensional compressible flow stability model is presented in this paper, which focuses on stall inception of multi-stage axial flow compressors with a finite large radius annular duct configuration for the first time. It is shown that under some
LIU, Xiaohua   +3 more
core   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Suppression of Performance Curve Instability of an Axial-Flow Pump by Using a Double-Inlet-Nozzle

open access: yesInternational Journal of Rotating Machinery, 2008
It has been shown that the sudden decrease of pump head in an axial flow pump caused by stall can be overcome by means of casing treatment. Flat axial grooves in front of the impeller break the swirl of the near-casing backflow.
P. Pérez Flores, G. Kosyna, D. Wulff
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Investigation of Blade Tip Interaction with Casing Treatment in a Transonic Compressor - Part 2: Numerical Results

open access: yes, 2008
A single-stage transonic axial compressor was equipped with a casing treatment, consisting of 3.5 axial slots per rotor pitch in order to investigate its influence on stall margin characteristics as well as on the rotor near tip flowfield both ...
Mönig, Reinhard   +4 more
core   +1 more source

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