Results 181 to 190 of about 514,126 (359)

In Situ Immunodetection of Neuronal Caspase-3 Activation in Alzheimer Disease [PDF]

, 1999
Lee A. Selznick, David M. Holtzman, Byung Hee Han, Murat Gökden, Anu Srinivasan, Eugene M. Johnson, Kevin A. Roth   +6 more
openalex   +1 more source

Homeostasis of Gut Microbiota Protects against Susceptibility to Fungal Pneumonia

Advanced Science, EarlyView.
Fungal pneumonia induces inflammation, shown by heightened IL‐6, IL‐1β, TNF‐α levels and a growth in Staphylococcus in the alveolar flora. The gut microbiota, acting through the gut‐lung axis via blood, impacts fungal pneumonia susceptibility by altering lung metabolism and inflammatory responses.
Jian Ji, Yongli Ye, Jiadi Sun, Lina Sheng, Jinyou Li, Jin Yang, Bing Wu, Yuting Wang, Xingxing Gao, Liang Luo, Jianfeng Ping, Yinzhi Zhang, Xiulan Sun   +12 more
wiley   +1 more source

Emodin Alleviates Sepsis‐Induced Multiorgan Damage by Inhibiting NETosis through Targeting Neutrophils BCL‐10

Advanced Science, EarlyView.
Emodin targets BCL‐10 to modulate the BCL‐10/MALT1 complex, thereby suppressing NF‐κB activation and significantly exerting multiorgan protective effects in sepsis. Abstract Sepsis is a life‐threatening condition caused by dysregulated host responses to infection, characterized by excessive inflammation and abnormal coagulation.
Xiaolong Xu, Yumeng Yan, Meiling Zheng, Mina Zhang, Tengfei Chen, Zhicheng Qu, Yinglu Bai, Shuwen Zhang, Chunming Zhao, Yifan Shi, Yan Lin, Ning Wang, Yunjing Bai, Yating Zhai, Zhaofang Bai, Wei Guo, Qingquan Liu   +16 more
wiley   +1 more source

T3SS effector EseJ in Edwardsiella piscicida inhibits PANoptosis in macrophages. [PDF]

Commun Biol
He TT, Tang PY, Jiang XL, Sun SS, Nie P, Xie HX.   +5 more
europepmc   +1 more source

Okanin Suppresses the Growth of Colorectal Cancer Cells by Targeting at Peroxiredoxin 5

Advanced Science, EarlyView.
Okanin suppresses colorectal cancer growth by directly targeting PRDX5. This natural compound selectively binds peroxiredoxin 5 (PRDX5), inhibiting its activity and inducing WSB1‐mediated degradation. PRDX5 loss elevates ROS, suppresses GPX4 via SIAH2, and further triggers cell death (apoptosis and ferroptosis).
Ji Zhong Zhao, Yuan Fei Li, Fu Kang Yuan, Meng Lu Zhao, Ya Wen Han, Jia Xin Wang, Qi Yang, Han Ying Ye, Yu Cheng Lu, Shao Chin Lee   +9 more
wiley   +1 more source

From mechanisms to markers: role of pyroptosis in revolutionizing thyroid cancer care. [PDF]

Cell Death Discov
Wang N, Chen Y, Luo G, Luo D.
europepmc   +1 more source

Mutant Huntingtin Expression in Clonal Striatal Cells: Dissociation of Inclusion Formation and Neuronal Survival by Caspase Inhibition

, 1999
Manho Kim, H-S Lee, Genevieve Laforet, Charmian McIntyre, Eileen J. Martin, Patrick Chang, Tae Wan Kim, Michael Williams, P. Hemachandra Reddy, Dan Tagle, Frederick M. Boyce, Lisa Won, Alfred Heller, Neil Aronin, Marian DiFiglia   +14 more
openalex   +1 more source

Caspase functions in cell death and disease.

Cold Spring Harbor Perspectives in Biology, 2013
D. Mcilwain, T. Berger, T. Mak
semanticscholar   +1 more source

Lifespan‐Regulated CAR‐Macrophages from Myeloid Progenitors for Enhanced Colorectal Cancer Therapy

Advanced Science, EarlyView.
Using a tamoxifen‐inducible Hoxb8 system, proliferative bone marrow progenitors can be generated, which are subsequently engineered with an anti‐CEA CAR construct containing a suicide gene (iCas9) and differentiated into CAR‐macrophages. This method facilitates scale up the production of CAR‐macrophages.
Chuancheng Gao, Fangling Hong, Yao Dong, Yong Fu, Yunong Ma, Xuedi Sun, Junfeng Zhang, Jiangning Chen, Zhen Huang   +8 more
wiley   +1 more source

Atypical contribution of caspase-3 to melanoma cancer cell motility by regulation of coronin 1B activity. [PDF]

Cell Death Dis
Berthenet K, Diazzi S, Jamard C, Stopa KB, Gil C, Dragan S, Fanfone D, Nguyen TT, Al N, Virard F, Meurette O, Popgeorgiev N, Hernandez-Vargas H, Ablain J, Ichim G.   +14 more
europepmc   +1 more source