HARMLESS Early Warning System for Advanced Materials
Advanced Sustainable Systems, EarlyView.The HARMLESS Early Warning System tackles Advanced Materials (AdMa) risk governance by providing a framework, organised in two tiers, underpinned with methods/tools to support risk assessors in the pre‐assessment preceding risk assessment. It allows for initial screening to identify AdMa with concerns considering exposure, hazards, sustainability and ...
Julia Prinz +11 more
wiley +1 more source
Caspase activation in the terminal differentiation of human epidermal keratinocytes [PDF]
, 1999 Miguel Weil, Martin Raff, Vania Braga
openalex +1 more source
Heterogeneity Landscape of Circulating Tumor Cells in Clinical Utility
Advanced Therapeutics, EarlyView.This study reports the heterogeneity spectrum of circulating tumor cells. The factors involved in the spectrum promote CTCs to overcome barriers in the metastatic cascade but impact the clinical outcome of cancer patients. In summary, the heterogeneities in association with CTCs ultimately reduce patient survival and facilitate increasing mortality of ...
Md Kowsar Alam +5 more
wiley +1 more source
Interleukin-18 Regulation of Interferon γ Production and Cell Proliferation as Shown in Interleukin-1β–Converting Enzyme (Caspase-1)-Deficient Mice [PDF]
, 1998 Giamila Fantuzzi +4 more
openalex +1 more source
Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy
Advanced Therapeutics, EarlyView.This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar +7 more
wiley +1 more source
Integrated real-time imaging of executioner caspase dynamics, apoptosis-induced proliferation, and immunogenic cell death using a stable fluorescent reporter platform. [PDF]
Cell Death DiscovSelcen S +7 more
europepmc +1 more source
Understanding miR‐200c: an Important Player in Resistance to Cancer Treatment
Advanced Therapeutics, EarlyView.How can one microRNA alter cancer's response to therapy? miR‐200c plays a central role in therapeutic resistance by modulating epithelial‐mesenchymal transition, apoptosis, cancer stemness features, and drug efflux. This review outlines the context‐dependent functions of miR‐200c in various cancers and highlights its potential as both a biomarker and a
Fatma Sanli, Omer Faruk Karatas
wiley +1 more source
Anti-apoptotic oncogenes prevent caspase-dependent and independent commitment for cell death [PDF]
, 1998 Gustavo P. Amarante‐Mendes +5 more
openalex +1 more source
Advanced Science, EarlyView.Treatment of MPTP‐incubated cells with NAD+‐boosters increase the UPRmt/mitophagy‐related mitochondria quality control (MQC). Disturbed plasma UPRmt‐mitophagy‐mediated MQC profiles in PD patient samples. NMN inhibits motor deficit and forestalls neuropathology phenotypes of PD mice, which is required the atf4‐medicated UPRmt pathway.
Shuoting Zhou +16 more
wiley +1 more source
RIPK1 kinase drove brain microvascular endothelial cells death and blood-brain barrier disruption in neonatal Escherichia coli meningitis. [PDF]
Nat CommunWang X +10 more
europepmc +1 more source