Results 271 to 280 of about 526,882 (310)

Caspase-8 expression in CD8⁺ T cells promotes pathogen restriction in the brain during <i>Toxoplasma gondii</i> infection. [PDF]

Sci Adv
Sibley LA, Cowan MN, Kelly AG, Amadi NA, Babcock IW, Labuzan SA, Kovacs MA, Batista SJ, Lukens JR, Harris TH.   +9 more
europepmc   +1 more source

DNMT2‐m5C‐ACLY Axis Promotes Lenvatinib Resistance in Hepatocellular Carcinoma Through Histone Acetylation‐Mediated Notch Pathway

Advanced Science, EarlyView.
Lenvatinib resistance poses a major challenge in advanced hepatocellular carcinoma (HCC). This study reveals that DNMT2 upregulation is a key driver, which stabilizes ACLY mRNA via m5C modification and activates the Notch signaling pathway. Crucially, combining ACLY inhibitors with lenvatinib overcomes resistance and suppresses tumors, offering a ...
Shiguang Yang, Jie Li, Shengwei Mao, Xuhui Zhao, Douwaner Liu, Jiafeng Chen, Jialu Fu, Yichao Bu, Xiaoling Wu, Shaoqing Liu, Qifeng Yu, Qiongzhu Dong, Zheng Tang, Yuan Fang, Yinghong Shi   +14 more
wiley   +1 more source

Effect of 12 Weeks of Treadmill Aerobic Training on Cytochrome c and Caspase-9 gene Expression in Cardiac Muscle of Male Rats

, 2017
Nasrin Javid Tabrizi, Jabbar Bashiri, Mohammad Narimani Rad   +2 more
openalex   +1 more source

Screening the Active Phytochemicals From <i>Eclipta prostrata</i> and Unraveling Their Molecular Insight Into Human Malignancies. [PDF]

Cancer Innov
Hossain MS, Khatun S, Mia MM, Zohora F, Sarker MR, Tanjida Islam KM, Sayeed MA, Mou MA, Hamidu S, Hamidu F, Wasaf Hasan AM, Mumtaj S, Hossain MK, Sohel M.   +13 more
europepmc   +1 more source

Elevated anti-apoptotic shift in primary human aniridia limbal stromal cells following 48 hours supraphysiological glucose exposure, in vitro. [PDF]

PLoS One
Liu S, Li S, Hsu SL, Fries FN, Li Z, Kundu S, Seitz B, Amini M, Suiwal S, Stachon T, Szentmáry N.   +10 more
europepmc   +1 more source

Caspase-3 deficiency inhibits the development and anti-tumor response of bone marrow-derived dendritic cells. [PDF]

Discov Oncol
Liu J, Du K, Chen Y, Zheng G, Zhang H, Zhang W, Hu X, Feng F.   +7 more
europepmc   +1 more source

Neuronal inflammasomes: balancing immunity, neuroinflammation, and homeostasis. [PDF]

Trends Immunol
de Rivero Vaccari JP, Keane RW.
europepmc   +1 more source

Lenvatinib Suppresses Colorectal Cancer Cell Growth, Migration, and Invasion <i>via</i> Dual-pathway Apoptosis and ERK/STAT3/NF-κB Inactivation. [PDF]

In Vivo
Wu CH, Hsu FT, Chen CH, Wang PE, Huang HY, Hsieh LL, Chen CH.   +6 more
europepmc   +1 more source