Results 291 to 300 of about 746,982 (336)

RBPMS2 can inhibit the NLRP3 / caspase-1 / GSDMD signaling pathway to resist pyroptosis in gastric cancer cells. [PDF]

Sci Rep
Zhang N, Yan L, Cao H, Zhang N, Zhang T, Guan S, Liu Q.   +6 more
europepmc   +1 more source

Apparent caspase independence of programmed cell death in Dictyostelium

, 1998
Robert A. Olie, Françoise Durrieu, Sophie Cornillon, Gary Loughran, Julian D. Gross, William C. Earnshaw, Pierre Golstein   +6 more
openalex   +1 more source

Gasdermin D‐Mediated Pyroptosis Exerts Two Opposite Effects of Resisting Enzymatic Digestion and Expanding Inflammatory Response in Acute Pancreatitis

Advanced Science, EarlyView.
Gasdermin D (GSDMD) does not only reduce pancreatic enzyme synthesis but also induces pancreatic acinar cells to express mucin 1 (MUC1), which forms a barrier to prevent digestive enzyme‐mediated digestion. However, GSDMD can promote the secretion of inflammatory cytokines by macrophages and aggravate pancreatic histological injury by expanding ...
Chaoxu Liu, Ning Liang, Chen Wu, Zhaoyan Qiu, Qian Huang, Xiaolong Wei, Shurong Zhang, Shuanghong Lei, Tao Yang, Gang Wang, Qian Wang   +10 more
wiley   +1 more source

Discovery of pyroptosis-inducing natural products in neuroblastomas: computational studies with experimental validation. [PDF]

BMC Complement Med Ther
Lestari B, Utomo RY, Rahman FA, Putri DDP, Zulfin UM, Suenaga Y, Meiyanto E, Hippo Y.   +7 more
europepmc   +1 more source

Farnesyltransferase inhibitors induce cytochrome c release and caspase 3 activation preferentially in transformed cells

, 1998
Nobutaka Suzuki, Jun Urano, Fuyuhiko Tamanoi   +2 more
openalex   +1 more source

Small Extracellular Vesicles Orchestrate Cisplatin‐Induced Ototoxicity: Potential Biomarker and Targets Discovery

Advanced Science, EarlyView.
Cisplatin causes reactive oxygen species accumulation, leading to apoptosis and inflammation in cochlear hair cells. Small extracellular vesicles primarily derived from the damaged hair cells likely contribute to cisplatin‐induced ototoxicity, carrying a variety of microRNAs and proteins.
Jingru Ai, Shasha Zhang, Mingchen Dai, Pei Jiang, Jingyuan Huang, Hairong Xiao, Yanqin Lin, Xujun Tang, Wei Tong, Jun He, Qiuyue Mao, Yintao Wang, Zixuan Ye, Tian Wang, Renjie Chai   +14 more
wiley   +1 more source

ANTP-SmacN7 enhances radiosensitivity in TPC-1 cells through XIAP-mediated activation of apoptotic protein. [PDF]

Sci Rep
Wang C, Zhang L, Wen K, Liu Q, Li Z, Yu P, Wen S, Zhang Y.   +7 more
europepmc   +1 more source

EBBP‐Mediated Integrated Stress Response Attenuates Anthracycline‐Induced Cardiotoxicity by Inhibiting the Ferroptosis of Cardiomyocytes

Advanced Science, EarlyView.
EBBP expression is significantly upregulated in DOX‐treated cardiomyocytes. Mechanistically, EBBP interacts with GRP78 to mediate K63‐linked ubiquitination, thereby attenuating the inhibitory GRP78‐PERK interaction and triggering activation of the PERK‐mediated integrated stress response (ISR).
Zilong Chen, Can Chen, Yichen Wu, Yinxue Xia, Ruijie Luo, Jiangcheng Shu, Long Chen, Zhaohui Wang, Cheng Wang, Kai Huang   +9 more
wiley   +1 more source

Mechanisms and interventions in aneurysmal subarachnoid hemorrhage: Unraveling the role of inflammatory responses and cell death in early brain injury (Review). [PDF]

Mol Med Rep
Lin R, Guan S, Wang J, Han M, Fan M, Wan J, Zhang X, Zhang N, Li J.   +8 more
europepmc   +1 more source