Results 191 to 200 of about 28,829 (241)
Some of the next articles are maybe not open access.
Drugs, 2001
Caspofungin is the first in a new class of antifungal agents, the glucan synthesis inhibitors, that interfere with fungal cell wall synthesis. Caspofungin exhibited in vitro and in vivo efficacy against a wide range of fungi and yeasts including Aspergillus and Candida species.
G M, Keating, B, Jarvis
+6 more sources
Caspofungin is the first in a new class of antifungal agents, the glucan synthesis inhibitors, that interfere with fungal cell wall synthesis. Caspofungin exhibited in vitro and in vivo efficacy against a wide range of fungi and yeasts including Aspergillus and Candida species.
G M, Keating, B, Jarvis
+6 more sources
Mycoses (Berlin), 2023
We evaluated the activity of amphotericin B, itraconazole, posaconazole, voriconazole and caspofungin against 1468 invasive moulds collected worldwide from 2018 to 2021. Most (>92%) of the Aspergillus spp.
M. Pfaller +2 more
semanticscholar +1 more source
We evaluated the activity of amphotericin B, itraconazole, posaconazole, voriconazole and caspofungin against 1468 invasive moulds collected worldwide from 2018 to 2021. Most (>92%) of the Aspergillus spp.
M. Pfaller +2 more
semanticscholar +1 more source
Drugs of Today, 2002
Available systemically effective antifungal agents for the treatment of invasive fungal infections are few. With the increasing recognition of a need for newer antifungal drugs, caspofungin has been introduced as the first member of a new class of compounds called echinocandins.
P H, Chandrasekar, E K, Manavathu
openaire +3 more sources
Available systemically effective antifungal agents for the treatment of invasive fungal infections are few. With the increasing recognition of a need for newer antifungal drugs, caspofungin has been introduced as the first member of a new class of compounds called echinocandins.
P H, Chandrasekar, E K, Manavathu
openaire +3 more sources
Medical Mycology, 2021
Candida auris is an emergent nosocomial multi-drug-resistant yeast that represents a global health threat. Recently, C. auris clinical isolates with caspofungin resistance were identified. Mutation in FKS1 gene was determined as a mechanism of resistance.
Bahgat Fayed, M. Jayakumar, S. Soliman
semanticscholar +1 more source
Candida auris is an emergent nosocomial multi-drug-resistant yeast that represents a global health threat. Recently, C. auris clinical isolates with caspofungin resistance were identified. Mutation in FKS1 gene was determined as a mechanism of resistance.
Bahgat Fayed, M. Jayakumar, S. Soliman
semanticscholar +1 more source
Expert Review of Anti-Infective Therapy, 2021
Introduction Candida species have been regarded as global health threats due to their ability to cause invasive infections. It is challenging to treat Candida bloodstream infections, which are associated with high mortality levels.
S. Su +6 more
semanticscholar +1 more source
Introduction Candida species have been regarded as global health threats due to their ability to cause invasive infections. It is challenging to treat Candida bloodstream infections, which are associated with high mortality levels.
S. Su +6 more
semanticscholar +1 more source
Antimicrobial Agents and Chemotherapy, 2020 Little is known about the influence of extracorporeal membrane oxygenation (ECMO) on the pharmacokinetics (PK) of caspofungin. The aim of this study was to describe population PK of caspofungin in patients with and without ECMO during the postoperative ...
Qianlin Wang, Zhu Zhang, Donglin Liu
exaly +2 more sources