Editorial: Advances in novel pharmacotherapeutics and drug discovery: computational, experimental, translational, and clinical models, volume II. [PDF]
Sandoval-Vásquez C +3 more
europepmc +1 more source
Real‐World Use of Avacopan in Antineutrophil Cytoplasmic Antibody–Associated Vasculitis: Early and Long‐Term Clinical, Renal, and Patient‐Reported Outcomes in an Italian Rheumatology–Nephrology Network [PDF]
Objective Complement activation, particularly through the C5a–C5a receptor axis, plays a pivotal role in the pathogenesis of antineutrophil cytoplasmic antibody–associated vasculitis (AAV) and may represent an important therapeutic target. Avacopan, an oral C5a receptor antagonist, was the first therapy targeting this pathway to enter in clinical ...
Quartuccio L +32 more
europepmc +2 more sources
Photochromism of Dicyanorhodanine-Pyrrole Conjugates: Substituent and Solvent Effects. [PDF]
Das P +4 more
europepmc +1 more source
Effects of Mineralogical Inhomogeneity on Aggregate Dust Optical Properties and Lidar Observables
Abstract Dust aerosols comprise irregular grains and aggregates with various mineralogical mixtures. However, most optical models use effective refractive indices to represent particles. This study develops an inhomogeneous aggregate model assigning mineral‐dependent refractive indices to constituent elements and representing global mineral volume ...
Dongchen Li, Ping Yang
wiley +1 more source
Human Tamm-Horsfall protein as a novel antitumor therapy for triple negative breast cancer and other solid tumors. [PDF]
Mercogliano MF +8 more
europepmc +1 more source
Evaluation and Classification of Atrial Arrhythmias from Signatures in Electrographic Flow Metrics. [PDF]
Castellano S +5 more
europepmc +1 more source
Ligand engineering enables precise control of emission in linear Cu(I) complexes by tuning donor–acceptor interactions between electron‐rich amines and π‐accepting mesoionic carbenes. Naphthyl‐substituted carbenes promote locally excited phosphorescence with vibronic structure, whereas electron‐rich amides combined with electron‐poor carbenes favor ...
Felix León +7 more
wiley +1 more source
Necrotizing Fasciitis of the Forearm in a 68-Year-Old Patient Treated with Split-Thickness Skin Graft: A Case Report. [PDF]
Porter S +4 more
europepmc +1 more source

