Results 181 to 190 of about 578,452 (308)
Correction: Synaptonemal & CO analyzer: a tool for synaptonemal complex and crossover analysis in immunofluorescence images. [PDF]
Soriano J +2 more
europepmc +1 more source
Rapid generation of prion disease models using AAV‐delivered PrP variants in knockout mice
We developed a rapid AAV‐based system to generate prion disease models in weeks rather than months. Following systemic AAV9P31 delivery of modified PrP to knockout mice, we achieved brain‐wide expression and successful propagation of both classical (RML) and atypical (GSS‐A117V) prion strains.
Maitena San‐Juan‐Ansoleaga +11 more
wiley +1 more source
Huntingtin in the amygdaloid basolateral complex is correlated with Vonsattel staging in Huntington's disease. [PDF]
Sanchez-Migallon P +10 more
europepmc +1 more source
A single amino acid change (L108I) combined with PrP overexpression drives spontaneous atypical prion formation in mice, enabling also efficient propagation of diverse prion strains. This model allows studying how spontaneous prion diseases arise and provides powerful tools for investigating strain emergence, transmission barriers, and mechanisms ...
Hasier Eraña +20 more
wiley +1 more source
Unwanted loneliness in older adults: sociodemographic, economic and psychosocial determinants and self-reported loneliness-inducing situations. [PDF]
Martínez-Ochoa ME +3 more
europepmc +1 more source
Abstract Biodiversity is globally threatened by human impacts, including land‐use transformation and climate change, which has prompted a rapid transition from fossil fuels to cleaner energy sources, such as photovoltaic (PV) energy. However, utility‐scale PV plants require vast areas and can lead to conflicts with biodiversity conservation, making ...
Pablo Medrano‐Vizcaíno +10 more
wiley +1 more source
Papel. - Artículo publicado en El Noticiero Bilbaíno (Bilbao). - Procedencia: fondo Miguel de Unamuno. - Conservación: Buena.
openaire +1 more source
Sensitization to propolis, shellac and gallate mix is FFA‐associated, but its relevance is largely unknown. Sensitization to salicylates is frequent and associated with symptoms of intolerance to sun exposure or sunscreens. No significant improvement by allergen avoidance is identified.
María‐Antonia Pastor‐Nieto +11 more
wiley +1 more source
Does nature shape risk preferences? Evidence from Chile, Norway, and Tanzania
Abstract Does exposure to a more risky environment affect risk preferences? Going beyond single‐case study evidence, we report results from five surveys conducted in three countries and link this with administrative data to study whether a link between exposure and preferences is detectable and widespread. We find no evidence for endogenous preferences
Florian Diekert, Robbert‐Jan Schaap
wiley +1 more source

