Results 121 to 130 of about 510,284 (301)

Safety of Baricitinib for the Treatment of Atopic Dermatitis in Adults Over a Median of 1.6 and up to 4.6 Years Treatment: Final Integrated Analysis of Eight Clinical Trials

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Baricitinib is a selective Janus kinase (JAK)1/JAK2 inhibitor approved in more than 70 countries for the treatment of moderate‐to‐severe atopic dermatitis (AD) in adults, and in over 30 countries for adolescents and children from age 2 years with moderate‐to‐severe AD, who are candidates for systemic therapy.
Antonio Costanzo, Antonio Torrelo, Eric L. Simpson, Marjolein De Bruin‐Weller, Diamant Thaçi, Norito Katoh, Silvia Sabatino, Andrew Buchanan, Kasia Morawska, Samuel Ogwu, Karen Denning, Jonathan I. Silverberg   +11 more
wiley   +1 more source

Characteristics of Adult Patients With Atopic Dermatitis Initiating Biologics and Janus Kinase Inhibitors in the CorEvitas Atopic Dermatitis Registry

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Biologics and Janus kinase inhibitors (JAKi) are two advanced systemic treatment options for patients with atopic dermatitis (AD). The decision to initiate one of these therapies is complex and may be driven by many factors.
Eric L. Simpson, Linda Stein Gold, Seemal R. Desai, Alexandra K. Golant, Douglas DiRuggiero, Christian Fenske, Yolanda Muñoz Maldonado, Alvin H. Li, Zach Dawson, Kaylee Ho, Kayla Callahan, Gaia Gallo, Jonathan I. Silverberg   +12 more
wiley   +1 more source

Carbon, Nitrogen, and Corresponding Stable Isotope Signatures Reveal Channel Banks as Major Sediment Sources in a Tropical Agricultural Watershed

Land Degradation &Development, EarlyView.
ABSTRACT Uncertainties about the applicability of δ13C and δ15N as tracers of sediment sources in tropical river basins highlight the need for more in‐depth investigations of these isotopes. This study therefore assessed the effectiveness of δ13C and δ15N signatures in discriminating sediment sources in an agricultural catchment in Northeast Brazil ...
Fábio Farias Amorim, Yuri Jacques Agra Bezerra da Silva, Rennan Cabral Nascimento, Ygor Jacques Agra Bezerra da Silva, Angelo Jamil Maia, Tales Tiecher, Jean Paolo Gomes Minella, Yusheng Zhang, Hari Ram Upadhayay, Simon Pulley, Adrian L. Collins   +10 more
wiley   +1 more source

Catalyst‐Free Mass Polymerization and Characterization of Bio‐Polyhydroxhyurethanes Based on Resorcinol Bis(Cyclocarbonate)

Macromolecular Materials and Engineering, EarlyView.
Non‐isocyanate polyhydroxyurethanes (PHUs) were synthesized from resorcinol bis(cyclocarbonate) and eco‐friendly diamines under mild, catalyst‐free conditions. The resulting polymers were extensively characterized for their structural, thermal, and mechanical properties, as well as processability and adhesion performance.
Federico Olivieri, Noemi Faggio, Giovanni Dal Poggetto, Chiara Santillo, Roberto Avolio, Rachele Castaldo, Mariacristina Cocca, Maria Emanuela Errico, Marino Lavorgna, Gennaro Gentile   +9 more
wiley   +1 more source

Bio‐Based Epoxy Resins from Estragole: Achieving High Glass Transition Temperatures Comparable to DGEBA and Simultaneously Low Viscosities

Macromolecular Materials and Engineering, EarlyView.
Two novel bio‐based epoxy monomers, diglycidyl‐4‐allylphenol (DG‐4A) and triglycidyl‐diallylphenol (TG‐DA), derived from estragole (92% and 72% bio‐content), were synthesized and cured with isophorone diamin (IPDA) and 4,4´‐diaminodiphenyl sulfone (DDS). The resins show high Tgs, with DG‐4A reaching and TG‐DA exceeding DGEBA‐based systems. These resins
Florian Bauer, Elisabeth Schamel, Herbert Schlachter, Gerd Wehnert, Dominik Söthje   +4 more
wiley   +1 more source

Suppression of FENO with observed inhaled corticosteroid therapy in severe asthma: is it a useful test in clinical practice?

ERJ Open Research, 2019
Shoaib Faruqi, Sean Zhou, Joanne Thompson, Terry Robinson, Karen Watkins, Helena Cummings, Nicola Jackson, Anoop Prakash, Michael Crooks   +8 more
doaj   +1 more source

Fiber Reinforcement of Soft Spider Silk Hydrogels

Macromolecular Rapid Communications, EarlyView.
Along the development of matrices for biomedical applications, precise tuning of the biomaterial to interact with specific cell types/tissues is essential. The fabrication of fiber mesh‐reinforced soft hydrogels made of recombinant spider silk proteins allows for the adjustment of mechanical properties and hydrogel porosity, leading to improved cell ...
Christina Heinritz, Thomas Scheibel
wiley   +1 more source

Some love them, others hate them: Understanding farmers' tree planting decisions in Scotland

People and Nature, EarlyView.
Abstract Agroforestry is increasingly recognized as a sustainable agricultural land use system with potential to sequester carbon, create and repair habitats, enhance biodiversity and offer environmental and socio‐economic benefits, including improved agricultural productivity.
Albert Mvula, Katrin Prager, Josie Geris
wiley   +1 more source

Archaeological Findings of the 16th–17th Centuries from the Town of Trypillia and Its Historical Topography

Київські історичні студії
The article analyses the informative potential of archaeological materials of the 16–17th centuries from the territory of the town of Trypillia to reconstruct its historical topography.
Mariia Videiko
doaj   +1 more source

Identifying knowledge barriers to agroforestry adoption and co‐designing solutions to them

People and Nature, EarlyView.
Abstract Compared to monocultures, agroforestry can promote biodiversity, ecosystem functioning and climate resilience, whilst maintaining or enhancing production and profits. Despite this, uptake in temperate regions remains low. Knowledge gaps amongst land managers are a primary barrier to uptake, but little is known about which aspects of ...
Amelia S. C. Hood, Verena Scherfranz, Rosy E. Scholes, Erika Degani, Tom Staton, Alexa Varah, Lena Schaller, Alice L. Mauchline   +7 more
wiley   +1 more source