Unicentric form of Castleman´s disease, pitfalls of diagnosis and surgical treatment [PDF]
BackgroundCastleman´s disease is an extremely rare heterogenous lymphoproliferative pathology with a mostly benign behavior. It is a localized or generalized lymph node enlargement of an unknown aetiology.
Jiri Molacek +10 more
doaj +2 more sources
Castleman′s disease with paraneoplastic pemphigus
Castleman′s disease is a rare autoimmune disorder with varied clinical presentations. Castleman′s commonly involves mediastinum and hence it is thoracic in most of the reported cases. Paraneoplastic pemphigus (PNP) and myasthenia gravis can be associated
Dinesha +4 more
doaj +2 more sources
Persistent or recurrent Castleman′s disease - Look out for a lurking lymphoma!
Castleman′s disease, a rare condition of uncertain etiology clinically presents in isolated form or as a multicentric disease. The multicentric form can develop malignancies such as Kaposi′s sarcoma or lymphomas.
Shalinee Rao +4 more
doaj +2 more sources
Idiopathic Multicentric Castleman Disease Associated With Seronegative Erosive Chronic Polyarthritis: A Diagnostic Challenge [PDF]
ABSTRACT Idiopathic multicentric Castleman disease can rarely present with systemic inflammation and erosive seronegative polyarthritis. Awareness of this association helps prevent misdiagnosis and ensures appropriate immunosuppressive management based on clinicopathological and immunohistochemical correlation.
Lo B +9 more
europepmc +2 more sources
POEMS Syndrome: 2026 Update on Diagnosis, Risk-Stratification, and Management. [PDF]
ABSTRACT Disease Overview POEMS syndrome is a life‐threatening syndrome due to an underlying plasma cell neoplasm. The major criteria for the syndrome are polyneuropathy, clonal plasma cell disorder (PCD), sclerotic bone lesions, elevated vascular endothelial growth factor, and the presence of Castleman disease.
Dispenzieri A.
europepmc +2 more sources
Paraneoplastic Pemphigus/Paraneoplastic Autoimmune Multiorgan Syndrome Associated With Castleman Disease: Multidisciplinary Management of a Rare Life-Threatening Syndrome. [PDF]
ABSTRACT Refractory oral erosions or polymorphous eruptions should prompt evaluation for paraneoplastic pemphigus, particularly when associated with mediastinal masses. Early tumor excision, multidisciplinary care, and vigilant monitoring for bronchiolitis obliterans are essential to improve outcomes in Castleman disease–associated paraneoplastic ...
Sohail A, Evans J, Tabata M.
europepmc +2 more sources
Australian clinical practice guideline: diagnosis and treatment of idiopathic multicentric Castleman disease. [PDF]
Abstract Idiopathic multicentric Castleman disease (iMCD) is a rare condition. The pathogenesis is incompletely understood; however, interleukin‐6 (IL‐6) is a major mediator. The clinical presentation is heterogeneous, from mild constitutional symptoms to severe multi‐organ failure.
Talaulikar D +16 more
europepmc +2 more sources
Abdominal unicentric Castleman´s disease: a case report
Castleman´s disease is a rare disease characterized by benign lymphoepithelial proliferation. There are two forms: unicentric and multicentric Castleman´s disease. Mediastinal location is the most frequent.
Samir Bradai +9 more
doaj +1 more source
Unicentric Mesenteric Castleman’s Disease- A Diagnostic Quandary-A Case Report [PDF]
Castleman`s Disease (CD) is a rare lymphoproliferative disorder and a mesenteric location is unusual. The unicentric variety is more difficult to diagnose clinically and it requires a histopathological confirmation.
Rajeshwara K V +4 more
doaj +1 more source
Castleman’s disease is a rare lymphoproliferative disorder, comprising hyaline vascular elements, and plasma cells, which can be present in unicentric or multicentric forms. This disease rarely involves the orbit/eye globe.
Alejandra Raquel Billagra +4 more
doaj +1 more source

