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Castleman disease [PDF]

Rheumatology
Janine Qasim, Karthik Ramasamy
doaj   +3 more sources

Idiopathic Multicentric Castleman Disease Associated With Seronegative Erosive Chronic Polyarthritis: A Diagnostic Challenge [PDF]

Clin Case Rep
ABSTRACT Idiopathic multicentric Castleman disease can rarely present with systemic inflammation and erosive seronegative polyarthritis. Awareness of this association helps prevent misdiagnosis and ensures appropriate immunosuppressive management based on clinicopathological and immunohistochemical correlation.
Lo B, Kane B, Benjelloun F, Niang M, Kaïré I, Siddiki C, Razafimandimby A, Deme H, Dial C, Pouye A.   +9 more
europepmc   +2 more sources

Grading of Castleman Disease Histopathology with an Attention-Based Multiple Instance Learning Model [PDF]

Diagnostics
Background/Objectives: Castleman disease is a rare cytokine-driven lymphoproliferative disorder in which lymph node histopathology provides key diagnostic information.
Muir J. Morrison, Alnoor, Brendan O’Fallon, Ashley Hutchings, Mark Dewey, Paul English, Alexandra E. Rangel, Lauren M. Zuromski, Katie Knight, Anna Bowen, Kiera Kearns, Kristin Shaw, Janani Sankar, Oscar Silva, Peyman Z. Samghabadi, Olga K. Weinberg, Miguel D. Cantu, Yidan Xu-Monette, Archana Agarwal, Timothy M. Hanley, Kristin H. Karner, Madhu Menon, Rodney R. Miles, Jay L. Patel, Anna Shestakova, Peng Li, Nicholas C. Spies, Ken H. Young, David P. Ng, Robert S. Ohgami   +29 more
doaj   +2 more sources

Australian clinical practice guideline: diagnosis and treatment of idiopathic multicentric Castleman disease. [PDF]

Intern Med J
Abstract Idiopathic multicentric Castleman disease (iMCD) is a rare condition. The pathogenesis is incompletely understood; however, interleukin‐6 (IL‐6) is a major mediator. The clinical presentation is heterogeneous, from mild constitutional symptoms to severe multi‐organ failure.
Talaulikar D, Ng JY, Bryant A, Bosco A, Caterson HC, Giri P, Hissaria P, Harrison SJ, Lade S, Leslie C, Perram J, Prince HM, Radeski D, Rischmueller M, Wallington-Gates C, Weber N, Hoi A.   +16 more
europepmc   +2 more sources

Paraneoplastic Pemphigus/Paraneoplastic Autoimmune Multiorgan Syndrome Associated With Castleman Disease: Multidisciplinary Management of a Rare Life-Threatening Syndrome. [PDF]

Clin Case Rep
ABSTRACT Refractory oral erosions or polymorphous eruptions should prompt evaluation for paraneoplastic pemphigus, particularly when associated with mediastinal masses. Early tumor excision, multidisciplinary care, and vigilant monitoring for bronchiolitis obliterans are essential to improve outcomes in Castleman disease–associated paraneoplastic ...
Sohail A, Evans J, Tabata M.
europepmc   +2 more sources

Real-World Usage and Outcomes of Different Siltuximab Dosing Frequency in Idiopathic Multicentric Castleman Disease. [PDF]

Am J Hematol
American Journal of Hematology, Volume 101, Issue 8, Page 2033-2037, August 2026.
Nishimura Y, Estevez MS, Asad H, Habermann T, Dispenzieri A.   +4 more
europepmc   +2 more sources

Case report: A rare case of retroperitoneal mixed type unicentric Castleman disease [PDF]

Frontiers in Oncology
ObjectiveTo enhance the understanding, diagnosis, and management of retroperitoneal mixed type unicentric Castleman disease.MethodsThis report describes a case of retroperitoneal mixed type unicentric Castleman disease managed at our institution.
Jiajie Zhang, Jiajie Zhang, Jian Zhang, Jinhao Liu, Panying Zhang, Shoubin Li   +5 more
doaj   +2 more sources

Hyaline Vascular Castleman Disease Presenting as Occipital Scalp Swelling in a Child [PDF]

Journal of Indian Association of Pediatric Surgeons
Castleman disease (CD) is rare in children, especially with occipital scalp involvement. We report a 9-year-old girl with a long-standing, asymptomatic occipital swelling diagnosed as hyaline vascular Castleman disease post-excision. This case highlights
Sumona Bose, Abanti Das, Tummidi Santosh, Rama Saha   +3 more
doaj   +2 more sources

A model for crowdsourcing high-impact research questions for Castleman disease and other rare diseases

Orphanet Journal of Rare Diseases, 2023
Background There are approximately 10,000 rare diseases that affect around 30,000,000 individuals in the U.S.A., most of which do not have an FDA-approved treatment.
Ania Korsunska, Mileva Repasky, Mary Zuccato, David C. Fajgenbaum   +3 more
doaj   +1 more source

Abdominal unicentric Castleman´s disease: a case report

The Pan African Medical Journal, 2021
Castleman´s disease is a rare disease characterized by benign lymphoepithelial proliferation. There are two forms: unicentric and multicentric Castleman´s disease. Mediastinal location is the most frequent.
Samir Bradai, Amal Khsiba, Abdelwaheb Nakhli, Moufida Mahmoudi, Asma Ben Mohamed, Abir Chaabane, Emna Chelbi, Medhioub Mona, Lamine Hamzaoui, Mousadek Azouz   +9 more
doaj   +1 more source