Results 71 to 80 of about 24,360 (218)

Charting the course of Sjögren's disease: A historical analysis of scientific progress

European Journal of Oral Sciences, EarlyView.
Abstract Sjögren's disease (SjD) bears the name of the Swedish ophthalmologist Henrik Sjögren. His 1933 doctoral thesis on keratoconjunctivitis sicca ignited interest, yet much remains under debate. SjD is an autoimmune disorder that primarily affects the exocrine glands, particularly the salivary and lacrimal glands, leading to a dryness of the eyes ...
Diego Ustárroz Cantali, Fabiola Reis de Oliveira, Denise Cantarelli Machado, Moisés Evandro Bauer   +3 more
wiley   +1 more source

Castleman`s disease: clinical, histopathological and imunohistochemical characteristics [PDF]

, 2011
Catedra Morfopatologie, USMF „Nicolae Testemiţanu”, Laboratorul Morfologia Tumorilor, Institutul OncologicThis paper represents a case of Castleman`s disease, investigated clinically, histopathologically and immunohistochemicallly.
Cernîi, Anatol, Vataman, Vladimir, Canţîr, Evghenii   +2 more
core   +1 more source

Comparison of intestinal histopathological changes following teclistamab, BCMA‐directed CAR T, CD19‐directed CAR T and rituximab therapies

Histopathology, EarlyView.
This is a retrospective review of intestinal tract biopsies from patients treated with various cellular immunotherapies (BCMA and CD19‐directed CAR T, teclistamab and rituximab therapies). We found distinct but overlapping histologic patterns across treatment groups, with lamina propria plasma cell depletion, crypt apoptotic bodies and active ...
Olivia J Leung, Esther Baranov, Isairis Peralta Valerio, Robin Collingwood, Natalie Respond, Don Siegel, Pooja Devi, Kristen M. Stashek   +7 more
wiley   +1 more source

Possible roles of Epstein-Barr virus in Castleman disease

Journal of Cardiothoracic Surgery, 2009
Background Complete resection seemed to be curative in patients with Castleman disease of any location but the disease is likely to be reactive in its pathogenesis. The relation between Epstein-Barr virus and Castleman disease has not been elucidated. We
Liu Hung-Chang, Chen Chih-Hao, Hung Tzu-Ti, Liu Tsang-Pai   +3 more
doaj   +1 more source

Membranous nephropathy associated with multicentric Castleman’s disease that was successfully treated with tocilizumab: a case report and review of the literature

BMC Nephrology, 2021
Background Multicentric Castleman’s disease is a life-threatening disorder involving a systemic inflammatory response and multiple organ failure caused by the overproduction of interleukin-6. Although renal complications of Castleman’s disease include AA
Ryosuke Saiki, K. Katayama, Y. Hirabayashi, Keiko Oda, M. Fujimoto, Tomohiro Murata, A. Nakajima, K. Dohi   +7 more
semanticscholar   +1 more source

Single‐centre analysis of severe Coombs‐positive autoimmune haemolytic anaemia in an HIV‐endemic population

HIV Medicine, EarlyView.
Abstract Introduction Human immunodeficiency virus (HIV) is a rare cause of autoimmune haemolytic anaemia (AIHA) which requires prompt diagnosis and treatment. We compared clinical and laboratory findings in AIHA patients with and without HIV. Methods We included adults with severe AIHA (haemoglobin ≤8 g/dL) diagnosed at a tertiary academic centre ...
Kathleen O. De John, Karryn Brown, Jenna Bailey, Estelle R. Verburgh, Jessica J. Opie   +4 more
wiley   +1 more source

Enfermedad de Castleman. Reporte de un caso

Gaceta Médica Espirituana, 2023
Fundamento: La enfermedad de Castleman es un proceso poco común y se caracteriza por la proliferación de linfocitos no clonales. Objetivo: Describir la presentación clínica, diagnóstico y tratamiento de un paciente con enfermedad de Castleman ...
Yudelky Almeida Esquivel, María Antonia Guerrero Rodríguez, Karell Piñón García, Claudio Cabrera Almarales   +3 more
doaj  

Castleman’s Disease- A Case Report

Bangabandhu Sheikh Mujib Medical University Journal, 2012
Castleman’s disease(CD) is a heterogeneous group of lymphoproliferative disorders of uncertain cause presenting with lymphadenopathy. It is histologically and prognostically distinct from malignant lymph-node hyperplasia.
Md. Ismail Patwary, Md. Abed Hossain, Md. Matiur Rahman, Md. Ashfaqul Islam Chowdhury, Md. Khalilur Rahman, Md. Ruhul Kabir   +5 more
doaj   +1 more source

Is TAFRO syndrome a subtype of idiopathic multicentric Castleman disease?

American journal of hematology/oncology, 2019
Castleman disease (CD) is a rare lymphoproliferative disorder that can be unicentric or multicentric. Multicentric CD (MCD) is further subdivided into human herpesvirus type‐8‐associated, POEMS syndrome‐associated, and idiopathic (iMCD).
Shino Fujimoto, T. Sakai, H. Kawabata, N. Kurose, S. Yamada, K. Takai, S. Aoki, J. Kuroda, M. Ide, K. Setoguchi, Norifumi Tsukamoto, Haruka Iwao-Kawanami, T. Kawanami, S. Mizuta, T. Fukushima, Y. Masaki   +15 more
semanticscholar   +1 more source

Identifying and targeting pathogenic PI3K/AKT/mTOR signaling in IL-6-blockade-refractory idiopathic multicentric Castleman disease.

Journal of Clinical Investigation, 2019
BACKGROUND Idiopathic multicentric Castleman disease (iMCD) is a hematologic illness involving cytokine-induced lymphoproliferation, systemic inflammation, cytopenias, and life-threatening multi-organ dysfunction.
D. Fajgenbaum, Ruth-Anne Langan, A. Japp, H. Partridge, S. Pierson, Amrit P. Singh, Daniel J. Arenas, J. Ruth, C. Nabel, Katie Stone, M. Okumura, A. Schwarer, F. José, N. Hamerschlak, G. Wertheim, M. Jordan, A. Cohen, V. Krymskaya, A. Rubenstein, M. Betts, T. Kambayashi, F. van Rhee, T. Uldrick   +22 more
semanticscholar   +1 more source