Results 1 to 10 of about 13,750 (216)
RheumatologyAn understanding of the disease pathogenesis has led to the discovery of therapuetic agents that target human herpesvirus-8 replication, CD20, and IL-6 and IL-6R antibodies.
Janine Qasim, Karthik Ramasamy
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Nature Reviews Disease Primers, 2021 Castleman disease (CD), a heterogeneous group of disorders that share morphological features, is divided into unicentric CD and multicentric CD (MCD) according to the clinical presentation and disease course. Unicentric CD involves a solitary enlarged lymph node and mild symptoms and excision surgery is often curative.
Antonino Carbone +2 more
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Ear, Nose & Throat Journal, 2018 HIV-negative Castleman disease has been associated with autoimmune disease, collagen vascular disorders, pulmonary arterial hypertension, and glomerulopathy.
Cohn, Jason E, Zhou, Jing, Hu, Amanda
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Orphanet Journal of Rare Diseases, 2023 Background There are approximately 10,000 rare diseases that affect around 30,000,000 individuals in the U.S.A., most of which do not have an FDA-approved treatment.
Ania Korsunska +3 more
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Mayo Clinic Proceedings, 1995 To describe the two variants of Castleman's disease--the hyaline-vascular type and the plasma-cell type--and discuss the associated histologic features.We present a case of the hyaline-vascular type and review the literature.Castleman's disease was once thought to be localized and self-limited, but in recent years, reports have described a multicentric
H, Shahidi, J L, Myers, P A, Kvale
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Clinical Imaging, 2003 We present a case of retroperitoneal Castleman's disease of the hyaline vascular type, with unusual MR imaging findings, differing form reports to date, along with a review of the imaging findings in Castleman's disease.
Louis M, Germaine, Jeffrey H, Newhouse
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The Korean Journal of Hematology, 2012 Castleman and Towne described a disease presenting as a mediastinal mass resembling thymoma. It is also known as "giant lymph node hyperplasia", "lymph node hamartoma", "angiofollicular mediastinal lymph node hyperplasia", and "angiomatous lymphoid hyperplasia".
Saeed-Abdul-Rahman, Ibrahiem +1 more
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Abdominal unicentric Castleman´s disease: a case report
The Pan African Medical Journal, 2021 Castleman´s disease is a rare disease characterized by benign lymphoepithelial proliferation. There are two forms: unicentric and multicentric Castleman´s disease. Mediastinal location is the most frequent.
Samir Bradai +9 more
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Journal of Oral and Maxillofacial Pathology, 2020 Castleman's disease, a type of lymph node hyperplasia, usually occurs in the mediastinum and rarely presents in the cervical region as an asymptomatic solitary mass. Clinically, they are of two types-solitary and multi-centric. Most of the solitary types are asymptomatic with no associated symptoms, whereas the multi-centric type is associated with ...
Srivastava, Himanshu +3 more
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Respiratory Medicine Case Reports, 2020 It has been considered that idiopathic multicentric Castleman disease often involves pulmonary complications recognized as lymphocytic interstitial pneumonia.
Daijiro Nabeya +2 more
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