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Castleman disease [PDF]

Rheumatology
An understanding of the disease pathogenesis has led to the discovery of therapuetic agents that target human herpesvirus-8 replication, CD20, and IL-6 and IL-6R antibodies.
Janine Qasim, Karthik Ramasamy
doaj   +5 more sources

Novel insights and therapeutic approaches in idiopathic multicentric Castleman disease [PDF]

Blood, 2018
Castleman disease (CD) describes a heterogeneous group of hematologic disorders that share characteristic lymph node histopathology. Patients of all ages present with either a solitary enlarged lymph node (unicentric CD) or multicentric lymphadenopathy ...
David C Fajgenbaum
exaly   +3 more sources

CT of Castleman disease in the mediastinum

Radiology Case Reports, 2023
Castleman disease is a rare lymphoproliferative disease commonly occurring as a benign localized mass of lymph nodes in the mediastinum. Given that Castleman disease presents as asymptomatic or through non-specific thoracic symptoms, detection is ...
Elias Lugo-Fagundo, BS, Carolina Lugo-Fagundo, MD, Edmund M. Weisberg, MS, MBE, Elliot K. Fishman, MD   +3 more
doaj   +2 more sources

EBV+ and Kaposi's Sarcoma Herpesvirus-Associated Multicentric Castleman Disease in a Patient With HIV Infection: A Case Report. [PDF]

Case Rep Infect Dis
Multicentric Castleman disease is a rare proliferative disease of lymphoid tissue. It has rarely been reported in Asian countries, particularly in HIV‐positive patients. Here, we report a case of Kaposi’s sarcoma herpesvirus‐associated Multicentric Castleman disease (KSHV‐MCD).
Huang MY, Li Z, Zhang W, Chen HY, Liu J, Li CX.   +5 more
europepmc   +2 more sources

Castleman disease mimicking an adrenal tumor: A case report

Urology Case Reports, 2022
Castleman disease is a benign complex lymphoproliferative disease. The most common site is the mediastinum. In this paper, we present a case of Castleman disease in the adrenal gland, as a very rare region.A 29-year-old woman was referred to our clinic ...
Robab Maghsoudi, Behnam Shakiba, Mahshid Panahi, Asaad Moradi   +3 more
doaj   +2 more sources

Robotic Resection of Parapharyngeal Follicular Dendritic Cell Sarcoma With Castleman Disease. [PDF]

Laryngoscope
Parapharyngeal follicular dendritic cell sarcoma (FDCS) is rare and may occur with Castleman disease. We describe the successful transoral robotic resection of a parapharyngeal FDCS associated with Castleman disease, highlighting the role of the robotic approach in achieving tissue diagnosis and definitive treatment.
Huang L, Patel AM, Chao T, Carey RM.
europepmc   +2 more sources

Doppler findings In castleman disease - A rare case [PDF]

Indian Journal of Radiology and Imaging, 2006
Castleman′s disease is a rare, benign disease of unknown cause that induces reactive lymph node hyperplasia. It has two histologic subtypes: hyaline vascular and plasma cellular. A definitive diagnosis necessitates tissue biopsy.
S Raniga, C Shah, A Shrivastava, P Amin, P Patel   +4 more
doaj   +2 more sources

Clinical Presentation, Treatment, and Outcomes of 28 Patients With Castleman Disease: A Retrospective Analysis of an Italian Cohort. [PDF]

EJHaem
ABSTRACT Background Castleman disease (CD) encompasses a range of heterogeneous non‐clonal lymphoproliferative disorders, including unicentric (UCD), and multicentric (MCD) forms. The latter is subdivided into HHV‐8+ MCD, POEMS‐MCD, and idiopathic‐MCD, not otherwise specified (iMCD‐NOS).
Cristinelli C, Merli M, Lucioni M, Gotti M, Sciarra R, Rattotti S, Carpi F, Favrin G, Bianchi B, Neri G, Coscia M, Gambacorta M, Passamonti F, Paulli M, Arcaini L.   +14 more
europepmc   +2 more sources

Possible roles of Epstein-Barr virus in Castleman disease

Journal of Cardiothoracic Surgery, 2009
Background Complete resection seemed to be curative in patients with Castleman disease of any location but the disease is likely to be reactive in its pathogenesis. The relation between Epstein-Barr virus and Castleman disease has not been elucidated. We
Liu Hung-Chang, Chen Chih-Hao, Hung Tzu-Ti, Liu Tsang-Pai   +3 more
doaj   +2 more sources

A model for crowdsourcing high-impact research questions for Castleman disease and other rare diseases

Orphanet Journal of Rare Diseases, 2023
Background There are approximately 10,000 rare diseases that affect around 30,000,000 individuals in the U.S.A., most of which do not have an FDA-approved treatment.
Ania Korsunska, Mileva Repasky, Mary Zuccato, David C. Fajgenbaum   +3 more
doaj   +1 more source