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Current Opinion in Hematology, 2007
Castleman disease was initially described over 50 years ago as a benign localized mass of lymph nodes found primarily in the mediastinum of asymptomatic patients. Subsequently, additional types were recognized that extend the spectrum of this heterogeneous group of diseases. Optimal standard therapies have not been established. Currently, most patients
Anu, Dham, Bruce A, Peterson
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Castleman disease was initially described over 50 years ago as a benign localized mass of lymph nodes found primarily in the mediastinum of asymptomatic patients. Subsequently, additional types were recognized that extend the spectrum of this heterogeneous group of diseases. Optimal standard therapies have not been established. Currently, most patients
Anu, Dham, Bruce A, Peterson
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Castleman Disease Pathogenesis
Hematology/Oncology Clinics of North America, 2018Castleman disease (CD) describes a group of heterogeneous disorders with common lymph node histopathologic features, including atrophic or hyperplastic germinal centers, prominent follicular dendritic cells, hypervascularization, polyclonal lymphoproliferation, and/or polytypic plasmacytosis.
David C, Fajgenbaum, Dustin, Shilling
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Retroperitoneal Castleman's Disease
Urology, 2010A 56-year-old postmenopausal woman with a history of colon cancer status after left hemicolectomy presented to our institution with abdominal pain, early satiety, and weight loss. Computerized tomography scan showed a large, enhancing, fat-containing mass displacing the left kidney posteriolaterally suspicious for a retroperitoneal liposarcoma.
A Ari, Hakimi +3 more
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Journal of Pediatric Surgery, 2008
Castleman disease is a rare benign lymph node hyperplasia usually presenting as an asymptomatic mediastinal mass in children. It can present at any extrathoracic site where there is lymphoid tissue. The sites include retroperitoneum, mesentery, axilla, and pelvis. Mesenteric Castleman disease is very rare in children.
Ke Ren, Zhang, Hui Min, Jia
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Castleman disease is a rare benign lymph node hyperplasia usually presenting as an asymptomatic mediastinal mass in children. It can present at any extrathoracic site where there is lymphoid tissue. The sites include retroperitoneum, mesentery, axilla, and pelvis. Mesenteric Castleman disease is very rare in children.
Ke Ren, Zhang, Hui Min, Jia
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Histopathology, 1989
Castleman's disease is characterized by lymph node enlargement. There are two distinct histologic subtypes. Most patients are asymptomatic and under age 30, and a mediastinal or hilar mass is found incidentally on chest radiograph. The pathogenesis is unknown, but a chronic inflammatory process has been suggested by some investigators.
M A, Goldberg, S A, Deluca
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Castleman's disease is characterized by lymph node enlargement. There are two distinct histologic subtypes. Most patients are asymptomatic and under age 30, and a mediastinal or hilar mass is found incidentally on chest radiograph. The pathogenesis is unknown, but a chronic inflammatory process has been suggested by some investigators.
M A, Goldberg, S A, Deluca
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Kyobu geka. The Japanese journal of thoracic surgery, 2010
Castleman’s disease (CD) is a rare, benign lymphoproliferative disorder of lymph nodes that was first described by Dr. Benjamin Castleman in 1956. CD is also known as giant lymph node hyperplasia or angiofollicular hyperplasia.
Richard Flavin +3 more
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Castleman’s disease (CD) is a rare, benign lymphoproliferative disorder of lymph nodes that was first described by Dr. Benjamin Castleman in 1956. CD is also known as giant lymph node hyperplasia or angiofollicular hyperplasia.
Richard Flavin +3 more
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Advances in clinical pathology : the official journal of Adriatic Society of Pathology, 1999
Castleman's disease (CD) is a rare atypical lymphoproliferative disorder whose morphology, soon after the original presentation of Castleman et al., has been definitely subdivided in a hyaline vascular (HV) and plasma cell (PC) histopathological pattern, with intermediate variants.
PALESTRO G +3 more
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Castleman's disease (CD) is a rare atypical lymphoproliferative disorder whose morphology, soon after the original presentation of Castleman et al., has been definitely subdivided in a hyaline vascular (HV) and plasma cell (PC) histopathological pattern, with intermediate variants.
PALESTRO G +3 more
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2013
Castleman’s disease (CD) is an uncommon lymphoproliferative disorder. Its etiology is related to HHV-8 infection, with immunocompromised patients as the most vulnerable population. Patients with the multicentric variant of CD require systemic treatment but the disease course often includes severe complications or evolution into malignant neoplasm.
Mariapaola Cucinotta, Angelina Cistaro
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Castleman’s disease (CD) is an uncommon lymphoproliferative disorder. Its etiology is related to HHV-8 infection, with immunocompromised patients as the most vulnerable population. Patients with the multicentric variant of CD require systemic treatment but the disease course often includes severe complications or evolution into malignant neoplasm.
Mariapaola Cucinotta, Angelina Cistaro
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Hematology/Oncology Clinics of North America, 2018
Unicentric Castleman disease (UCD) is a rare lymphoproliferative disorder that manifests typically as proliferation of a single lymph node or region of lymph nodes. Histologically, hyaline vascular variant is found in a majority of UCDs. UCD commonly presents in younger patient populations. Patients with UCD may be asymptomatic or present with symptoms
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Unicentric Castleman disease (UCD) is a rare lymphoproliferative disorder that manifests typically as proliferation of a single lymph node or region of lymph nodes. Histologically, hyaline vascular variant is found in a majority of UCDs. UCD commonly presents in younger patient populations. Patients with UCD may be asymptomatic or present with symptoms
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1978
In 1956, Castleman studied a group of patients with “asymptomatic, large, benign hyperplastic mediastinal lymph nodes that resembled thymomas” [3]. Although a similar lesion was subsequently described by others under various designations including lymph nodal hamartoma [1], angiofollicular mediastinal lymph node hyperplasia [7], and benign lymphoid ...
R. F. Dorfman, M. Cibull
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In 1956, Castleman studied a group of patients with “asymptomatic, large, benign hyperplastic mediastinal lymph nodes that resembled thymomas” [3]. Although a similar lesion was subsequently described by others under various designations including lymph nodal hamartoma [1], angiofollicular mediastinal lymph node hyperplasia [7], and benign lymphoid ...
R. F. Dorfman, M. Cibull
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