Results 41 to 50 of about 1,529,345 (306)

TLR Agonist Nano Immune Therapy Clears Peritoneal and Systemic Ovarian Cancer

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Intraperitoneal administration of immunogenic Toll‐like receptor agonist‐modified mesoporous silica nanoparticles leads to rapid internalization by ascites myeloid cells with trafficking to fat‐associated lymphoid clusters. Activation of myeloid cells counters suppressive immune mechanisms associated with peritoneal metastasis, leading to regional and ...
Ben Marwedel, Henning De May, Lauren Anderson, Lorél Y. Medina, Ellie Kennedy, Erica Flores, John O'Rourke, Marian Olewine, Irina Lagutina, Lillian Fitzpatrick, Fred Shultz, Donna F. Kusewitt, Eric Bartee, Sarah Adams, Achraf Noureddine, Rita E. Serda   +15 more
wiley   +1 more source

Longer Acting Injectable: Continuous, Linear Release of a Progestin Contraceptive From an Oxidized Porous Silicon Host

Advanced Healthcare Materials, EarlyView.
Progestin drugs are loaded into a mesoporous silicon dioxide host by melt‐infiltration. Drugs that decompose at or close to their melting point can be loaded by the addition of cholesterol, which acts as a melting point suppressor. High mass loading of the drug is achieved, and dissolution of the composite is controlled by the nanoscale properties of ...
Geoffrey Hollett, Ruhan Fan, Tushar Kumeria, Heidi Leonard, Byungji Kim, Taylor R. Martin, Irmak Ipekci, Joanna Wang, Jiuk Byun, Nicole A. Chan, Amber Pierron, Curtis E. Moore, Jennifer Ayres, Michael J. Sailor   +13 more
wiley   +1 more source

Chemical modifications of castor oil: A review

Science in progress, 2019
The necessity of using petrochemicals for the development of polymers has been deteriorating because of the depletion in fossil fuels and environmental concerns such as the effect of greenhouse gases, global warming, and increasing population.
Ntsako Portia Chauke, H. E. Mukaya, D. Nkazi   +2 more
semanticscholar   +1 more source

Smart Polymeric 3D Microscaffolds Hosting Spheroids for Neuronal Research via Quantum Metrology

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Development of a platform consisting of 3D microscaffolds supporting 3D embryoid bodies for neuronal research. The polymeric scaffolds enable directed growth of neurites. This study shows nanodiamond‐based quantum sensors graft onto the polymer material, enabling quantum metrology experiments within the 3D neuronal model and thereby providing a ...
Beatriz N. L. Costa, Ana Marote, Catarina Barbosa, Jonas Campos, António J. Salgado, Jana B. Nieder   +5 more
wiley   +1 more source

Synthesis and properties of castor oil based plasticizers

RSC Advances, 2019
A series of environment-friendly plasticizers has been synthesized from castor oil through a mild esterification/epoxidation reaction. The modified epoxy acetylated castor oil (EACO) can plastify poly(vinyl chloride) (PVC) efficiently, even better than ...
Qinghe Fu, Yilang Long, Yingyun Gao, Yuan Ling, Hao Qian, F. Wang, Xinbao Zhu   +6 more
semanticscholar   +1 more source

Dexamethasone Delivery via Amphiphilic, Low‐swelling Hydrogels Treats Postoperative Inflammation in Cervical Spine Applications

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
DexaPatch, an implantable, low‐swelling amphiphilic hydrogel system containing dexamethasone‐PLGA microparticles, is developed and characterized for sustained local steroid release to reduce postoperative inflammation in tight surgical spaces. DexaPatch significantly reduces postoperative edema and fibrosis in a rabbit model of anterior spinal surgery,
Stephen W. Linderman, Graham F. Barber, S'Dravious A. DeVeaux, Edward A. Botchwey, Daniel Refai, Adam M. Klein, Andrés J. García   +6 more
wiley   +1 more source

High‐Throughput Encapsulation of Stem Cells: Characterizing Dynamic Culture Variability With a Millifluidic Approach

Advanced Healthcare Materials, EarlyView.
A high throughput millifluidic encapsulation platform is engineered and standardized. The system's output allows the monitoring of cell expansion in strong dynamic conditions. High polymer crosslinking leads to higher cell proliferation and lower cell growth on microgel's surface.
Oscar Fabian García‐Aponte, Marta Serra, Simon Kahlenberg, Guruprakash Subbiahdoss, Erik Reimhult, Dominik Egger, Cornelia Kasper   +6 more
wiley   +1 more source

Castor Oil for Induction of Labor

Obstetric Anesthesia Digest, 2009
Background:  Castor oil is one of the most popular drugs for induction of labour in a non‐medical setting; however, published data on safety and effectiveness of this compound to induce labour remain sparse.Aim:  To assess the safety and effectiveness of castor oil for induction of labour in pregnancies with an ultrasound estimated gestational at birth
Rose McGready, Rose McGready, Saw Oo Tan, Marcus J. Rijken, François Nosten, François Nosten, Mupawjay Pimanpanarak, MK Paw, Pratap Singhasivanon, Sue Jean Lee, Sue Jean Lee, Machteld E. Boel   +11 more
openaire   +7 more sources

Multienzyme (3‐in‐1)‐Mimicking a Single Nucleobase‐Derived Bionanozyme for Versatile Environmental and Biomedical Applications

Advanced Healthcare Materials, EarlyView.
This study reports the development of bioinspired 2D crystalline Bionanozyme derived from a single nucleobase. It effectively mimics multienzyme activity to detect and remove phenolic pollutants, identify disease biomarkers with high sensitivity, and protect cells from oxidative stress.
Subrat Vishwakarma, Om Shanker Tiwari, Durba Banerjee, Linda J. W. Shimon, Amit Israelstam, Ilia Kaminker, Sudip Mukherjee, Ehud Gazit, Pandeeswar Makam   +8 more
wiley   +1 more source

Advancing from MOFs and COFs to Functional Macroscopic Porous Constructs

Advanced Materials, EarlyView.
This review study investigates the recent progress and methodologies for manufacturing metal–organic framework (MOF) or covalent–organic framework (COF)‐based 3D structured macroscopic porous constructs with high structural integrity, providing the possibility to control their porosity across dimensions.
Seyyed Alireza Hashemi, Ahmadreza Ghaffarkhah, Ali Akbar Isari, Mahyar Panahi‐Sarmad, Feng Jiang, Orlando J. Rojas, Stefan Wuttke, Mircea Dincă, Mohammad Arjmand   +8 more
wiley   +1 more source