Results 241 to 250 of about 650,104 (308)

Quercetin Inhibits AKT Ser473 Phosphorylation and Disrupts AKT-Androgen Receptor Signaling in Castration-Resistant Prostate Cancer Cells. [PDF]

Antioxidants (Basel)
Duprat F, Azócar-Plaza S, Castillo-Cáceres MP, Rivas Y, Sanzana-Rosas J, Pampaloni P, Olivas-Henríquez G, Toledo J, Villa JL, Bertinat R, Jara N, Vallejos-Almirall A, Salas A, González-Chavarría I.   +13 more
europepmc   +1 more source

Identification of genetically predicted protein biomarkers and drug targets for prostate cancer via Mendelian randomization

VIEW, Volume 7, Issue 3, June 2026.
Prostate cancer, a leading cause of cancer in men globally, urgently requires improved diagnostic and treatment strategies. This study analyzed large genetic datasets and identified five key proteins (THBD, DST, IFI27L2, OSBPL10, PPP1R14A) that either increase or decrease cancer risk, while also exploring their roles in immune response and potential ...
Maoping Cai, Tianming Peng, Zhiyue Xie, Chuqian Zhen, Chen Yao, Nan Peng, Qianyi Li, Yuzhong Yu, Jiming Bao, Xian‐Lu Song, Mingkun Chen, Shan‐Chao Zhao   +11 more
wiley   +1 more source

Rethinking combination strategies in metastatic castration-resistant prostate cancer (mCRPC)-lessons from KEYNOTE-641. [PDF]

Transl Androl Urol
Nguyen MD, Vinh-Hung V, Verschraegen C, Wang P.   +3 more
europepmc   +1 more source

Synergistic RU486 and olaparib therapy enhances apoptosis in endometriosis by simultaneously targeting hormonal signalling and DNA repair

British Journal of Pharmacology, Volume 183, Issue 11, Page 2947-2968, June 2026.
Background and Purpose Endometriosis is a chronic, hormone‐dependent disorder characterized by ectopic implantation of endometrial tissue, often accompanied by pain and infertility. Although the progesterone receptor modulator RU486 is effective for pain relief, its impact on lesion regression is limited, possibly due to apoptosis resistance and ...
Yujie Peng, Meng Zhang, Libo Zhu, Wenqiang Qian, Jingjing Yan, Huidi Jiang, Yu Xin, Ying Zhang, Dongli Sun, Weidong Fei, Mengdan Zhao   +10 more
wiley   +1 more source

Bellmunt Risk Score as a Prognostic Tool in Metastatic Castration-Resistant Prostate Cancer Survival.

JAMA Netw Open
Büttner T, Klümper N, Ellinger J, Ritter M, Krausewitz P.   +4 more
europepmc   +1 more source

Efficacy of Early Switching From Docetaxel to Cabazitaxel in Castration-Resistant Prostate Cancer. [PDF]

Prostate
Kawai T, Maki K, Taguchi S, Fujii Y, Tanaka T, Miyakawa J, Kamei J, Kakutani S, Niimi A, Yamada D, Yamada Y, Takada T, Nakagawa T, Kume H.   +13 more
europepmc   +1 more source

Are We Willing to Change? A Feminist Agenda for the Study of Men in Families

Journal of Family Theory &Review, Volume 18, Issue 2, Page 285-297, June 2026.
ABSTRACT Public concern over the increasingly visible crisis of hegemonic masculinity is growing. Young men are showing a rise in antifeminist rhetoric, worsening mental health, and a loneliness epidemic. Although it is tempting, and not without merit, to frame men's struggles as male fragility and aggrieved entitlement resulting from feeling unseated ...
Aran Garnett‐Deakin, Caroline Sanner
wiley   +1 more source

Predictive value of interim ¹¹C-choline PET/CT for response to radium-223 in metastatic castration-resistant prostate cancer. [PDF]

EJNMMI Res
Ahmed EE, Andrews JR, Ahmed ME, Haloi R, Rhodes LA, Mahon M, Carter DA, Wei N, Thorpe MP, Johnson GB, Kwon ED, Kendi AT.   +11 more
europepmc   +1 more source

Silene, a versatile model system: from sex and genome evolution to ecology and speciation

New Phytologist, Volume 250, Issue 6, Page 3613-3630, June 2026.
Summary Fundamental and applied research in evolutionary biology benefits from the use of model systems in which approaches from disparate disciplines can be integrated. Here, we review recent progress in evolutionary research on the long‐standing model system Silene, a large genus with a well‐resolved phylogeny and newly available, expanded genomic ...
Sophie Karrenberg, Václav Bačovský, Andrea E. Berardi, Isabelle De Cauwer, Tatiana Giraud, Fanny E. Hartmann, Roman Hobza, Vojtěch Hudzieczek, Gabriel A.B. Marais, Jenna R. Miladin, Bengt Oxelman, Alexander S.T. Papadopulos, Daniel B. Sloan, Janet C. Steven, Helena Štorchová, Pascal Touzet, Fabienne Van Rossum   +16 more
wiley   +1 more source

Case Report: [²²⁵Ac]Ac-PSMA-617 therapy in a patient with metastatic castration-resistant prostate cancer (mCRPC) and intracranial meningioma. [PDF]

Front Oncol
Musabaev I, Goryaynov S, Yu Kochetova T, Krylov V, Ivanov S.   +4 more
europepmc   +1 more source