Results 101 to 110 of about 16,591 (206)

Intercellular Horizontal Transfer of TXNDC5 mRNA via Extracellular Vesicles Contributes to Tumor‐Associated Macrophage‐Mediated Prostate Cancer Metastasis

Advanced Science, Volume 13, Issue 13, 3 March 2026.
This study investigates the role of M2 macrophage‐derived extracellular vesicles (M2 EVs) in prostate cancer (PCa) metastasis. Mechanistically, M2 EVs horizontally transfer TXNDC5 mRNA to PCa cells, where the molecule induces the mesenchymal‐like state (MLS), enhancing PCa migration and invasion.
Cong Hu, Tianyang Wu, Jiayi Wang, Xinxing Du, Xinrui Wu, Yanhao Dong, Zehong Peng, Penghui Liao, Zirui Guo, Zheyu Liu, Kenneth J Pienta, Yinjie Zhu, Jiahua Pan, Liang Dong, Wei Xue   +14 more
wiley   +1 more source

Single‐Cell Morphomechanics of Prostate Cancer‐Associated Fibroblasts Identifies Distinct Features Associated with Patient Outcome

Advanced Science, Volume 13, Issue 13, 3 March 2026.
Cancer‐associated fibroblasts (CAFs) in prostate tumors exhibit distinct morphomechanical traits vs normal fibroblasts, including greater stiffness and volume, more elongated stress fibres, and larger and more elongated nuclei. These features, quantified through imaging and real‐time deformability cytometry, correlate with patient outcomes and can be ...
Antje Garside, Angela Jacobi, Shivakumar Keerthikumar, Vaibhav Mahajan, Michelle Richards, Birunthi Niranjan, Linda Teng, Nicholas Choo, Johannes Low Jun Wei, Gail P Risbridger, Mitchell G Lawrence, Anna V. Taubenberger   +11 more
wiley   +1 more source

Cytoreductive Radical Prostatectomy in Oligometastatic Prostate Cancer: Single‐Centre Experience

BJUI Compass, Volume 7, Issue 3, March 2026.
Abstract Objective This study aims to evaluate the oncological outcomes, functional recovery and overall satisfaction following cytoreductive radical prostatectomy (CRP) in patients with oligometastatic prostate cancer treated at a single tertiary‐care centre.
Khawaja Abdul Rouf, Akil Latief, Sajad Ahmad Para, Younis Mushtaq, Shubham Gupta, Sajad Ahmad Malik, Saqib Mehdi, Arif Hamid   +7 more
wiley   +1 more source

Extended versus limited pelvic lymph node dissection and long‐term outcomes in high‐risk prostate cancer before radiotherapy

BJUI Compass, Volume 7, Issue 3, March 2026.
Abstract Objectives To compare oncological outcomes after extended pelvic lymph node dissection (PLND) versus limited in patients with high‐risk prostate cancer (PCa) undergoing curative external beam radiation therapy (EBRT). Patients and Methods From 3627 men with PCa at a single centre between 2000 and 2013, 167 with high‐risk, age ≤75, Gleason ...
Georgios Daouacher, Jessica Carlsson, Pernilla Sundqvist, Mauritz Waldén   +3 more
wiley   +1 more source

Systematic Review of Genomic‐Based Risk Stratification in Localised Prostate Cancer Treatment Optimisation: Clinical Impact and Health Economic Evidence

Cancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT Background Several genomic risk stratification tests are available to predict the risk of metastasis and mortality for prostate cancer patients at the time of diagnosis. However, the evidence supporting the clinical utility of genomic risk stratification tools is fragmented, posing challenges in assessing their real‐world clinical impact and ...
Juntao Lyu, Fan He, Niall M. Corcoran, Gang Chen, Hadi Akbarzadeh Khorshidi   +4 more
wiley   +1 more source

Mausolate Complexes of the Alkaline Earth Metals

ChemistryEurope, Volume 4, Issue 3, March 2026.
Reliable chelation of Ra2+ for radionuclide therapy has long been a challenge, and the capacious and rigid mausolate ligand may offer a promising approach. We describe herein mausolate complexes with the chemically similar Ba2+, and other group 2 dications, including the introduction of functionalized derivatives. The rapid uptake of alkaline earth (Ae)
Jack F. Smart, Liam D. N. Krueckl, R. Quinn Schmidt, Leah Gajecki, Lindsey E. K. Frederiksen, Allen G. Oliver, David J. Berg, J. Scott McIndoe   +7 more
wiley   +1 more source

Epigenetic modulators as therapeutic targets in prostate cancer

Prostate cancer is one of the most common non-cutaneous malignancies among men worldwide. Epigenetic aberrations, including changes in DNA methylation patterns and/or histone modifications, are key drivers of prostate carcinogenesis.
Crabb, Simon J., Graça, Inês, Henrique, Rui, Jerónimo, Carmen, Packham, Graham, Pereira-Silva, Eva   +5 more
core   +1 more source

Pulmonary neuroendocrine (carcinoid) tumors: European Neuroendocrine Tumor Society expert consensus and recommendations for best practice for typical and atypical pulmonary carcinoids [PDF]

, 2017
This is an expert consensus from the European Neuroendocrine Tumor Society recommending best practice for the management of pulmonary neuroendocrine tumors including typical and atypical carcinoids.
Bartsch, Detlief, Bartsch, Detlief, Baudin, E., Capdevila, Jaume, Capdevila, Jaume, Caplin, M. E., Costa, Frederico, Costa, Frederico, Cwikla, Jaroslaw, Cwikla, Jaroslaw, de Herder, Wouter, de Herder, Wouter, Delle Fave, Gianfranco, Delle Fave, Gianfranco, Eriksson, Barbro, Eriksson, Barbro, Falconi, Massimo, Falconi, Massimo, Ferolla, P., Ferone, Diego, Ferone, Diego, Filosso, P., Garcia-Yuste, M., Gross, David, Gross, David, Grossman, Ashley, Grossman, Ashley, Ito, Tetsuhide, Ito, Tetsuhide, Jensen, Robert, Jensen, Robert, Kaltsas, Gregory, Kaltsas, Gregory, Kelestimur, Fahrettin, Kelestimur, Fahrettin, Kianmanesh, Reza, Kianmanesh, Reza, Knigge, Ulrich, Knigge, Ulrich, Kos-Kudla, Beata, Kos-Kudla, Beata, Krenning, Eric, Krenning, Eric, Lim, E., Mitry, Emmanuel, Mitry, Emmanuel, Nicolson, Marianne, Nicolson, Marianne, O'Connor, Juan, O'Connor, Juan, O'Toole, Dermot, O'Toole, Dermot, Oberg, K., Pape, Ulrich-Frank, Pape, Ulrich-Frank, Pavel, Marianne, Pavel, Marianne, Pelosi, G., Perren, A., Ramage, John, Ramage, John, Raymond, Eric, Raymond, Eric, Rindi, Guido, Rindi, Guido, Rockall, Andrea, Rockall, Andrea, Rossi, R. E., Ruszniewski, Philippe, Ruszniewski, Philippe, Salazar, Ramon, Salazar, Ramon, Scarpa, Aldo, Scarpa, Aldo, Sedlackova, Eva, Sedlackova, Eva, Sundin, Anders, Sundin, Anders, Toumpanakis, Christos, Toumpanakis, Christos, Travis, W. D., Vullierme, Marie-Pierre, Vullierme, Marie-Pierre, Weber, Wolfgang, Weber, Wolfgang, Wiedenmann, Bertram, Wiedenmann, Bertram, Zheng-Pei, Zeng, Zheng-Pei, Zeng   +88 more
core  

The multifaceted roles of the ACSL family in cancer: Metabolic reprogramming, ferroptosis regulation and tumour immune microenvironment remodelling

Clinical and Translational Medicine, Volume 16, Issue 3, March 2026.
The acyl‐CoA synthetase long‐chain (ACSL) family consists of five members, which exhibit a synergistic effect in promoting tumour lipid metabolism for energy supply. Specifically, ACSL3 and ACSL4 have antagonistic effects on the mechanisms related to ferroptosis in tumour cells.
Haocai Li, Weijian Wang, Juncheng Zhan, Yuxiang Xiao, Xiaoping Chen, Chen Su, Peng Zhu   +6 more
wiley   +1 more source

Arachis hypogaea L. Root Extract Mitigates Testosterone Propionate‐Induced Benign Prostatic Hyperplasia in ICR Mice by Suppressing Inflammation, Androgen Receptors, and Dihydrotestosterone

Food Science &Nutrition, Volume 14, Issue 3, March 2026.
In summary this study evaluated the protective effects of Arachis hypogaea L. root extract (AHRE) against testosterone propionate (TP)‐induced benign prostatic hyperplasia (BPH) in ICR mice. AHRE was prepared and administered in varying doses (100, 200, 300 mg/kg BW) alongside TP, with finasteride as a positive control.
Samee‐Ullah, Faryal Shaukat, Muhammad Umair Ijaz, Muhammad Bilal, Anees Ahmed Khalil, Tausif Ahmad, Yemin Guo, Xia Sun, Yuanda Song, Mohammed Mansour Quradha   +9 more
wiley   +1 more source