Results 101 to 110 of about 15,879 (168)

FOXA1 is a highly sensitive diagnostic marker for prostate cancer including small cell carcinoma of the prostate

open access: yesHistopathology, Volume 89, Issue 2, Page 240-250, August 2026.
FOXA1 is a highly sensitive diagnostic marker for prostate cancer. Besides prostatic adenocarcinoma, it is also expressed in 57%–80% of metastatic or primary prostatic small cell carcinomas, which lose traditional prostatic markers including NKX3.1. Although it is less specific than NKX3.1, it can serve as a valuable adjunct for confirming prostatic ...
Jianping Zhao   +11 more
wiley   +1 more source

[18F]PSMA‐1007 PET–Based Recurrence Site Distribution and Predictors of Metastatic Disease in Patients With Biochemical Recurrence of Prostate Cancer

open access: yesInternational Journal of Urology, Volume 33, Issue 8, August 2026.
ABSTRACT Objectives Prostate‐specific membrane antigen positron emission tomography (PSMA‐PET) is a sensitive imaging modality for detecting recurrent prostate cancer following definitive local therapy. However, evidence on 18F‐labeled PSMA tracers in Japanese patients with biochemical recurrence (BCR) remains limited.
Koji Hatano   +15 more
wiley   +1 more source

Real‐World Outcomes of Radium‐223 Therapy in Metastatic Castration‐Resistant Prostate Cancer: Predictive Value of PSA Doubling Time and Enzalutamide Continuation

open access: yesInternational Journal of Urology, Volume 33, Issue 8, August 2026.
ABSTRACT Background Radium‐223 dichloride (Ra‐223) is an effective treatment for metastatic castration‐resistant prostate cancer (mCRPC) with bone metastases. However, predictive factors associated with treatment efficacy remain unclear. This study evaluated prognostic factors associated with the efficacy of Ra‐223 and investigated outcomes according ...
Kodai Abe   +14 more
wiley   +1 more source

CDK12/13 Inhibition Induces DNA Hypomethylation and Sensitizes Cancer Cells to Compounds Targeting DNA‐PK

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 16, August 2026.
ABSTRACT Inactivation of the major transcription elongation kinase, cyclin‐dependent kinase 12 (CDK12), characterizes a subset of aggressive prostate cancers but it is not known how cells adapt and even benefit from this event. We show that mutations in the CDK12 gene are associated with decreased DNA methylation in patient tumours and dual inhibition ...
Jing Liang   +2 more
wiley   +1 more source

Topographical and stage-related expression of nectin-4 in prostate cancer. [PDF]

open access: yesCent European J Urol
Garaz R   +6 more
europepmc   +1 more source

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